High-Throughput Screening of FDA-Approved Drug Library Reveals Ixazomib Is a Broad-Spectrum Antiviral Agent against Arboviruses

High-Throughput Screening of FDA-Approved Drug Library Reveals Ixazomib Is a Broad-Spectrum Antiviral Agent against Arboviruses

The emergence of significant arboviruses and their spillover transmission to humans represent a major threat to global public health. No approved drugs are available for the treatment of significant arboviruses in circulation today. The repurposing of clinically approved drugs is one of the most rap...

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Bibliographic Details
Main Authors: Cuiling Ding, Wanda Tang, Binghui Xia, Haoran Peng, Yan Liu, Jiaqi Wang, Xu Zheng, Yangang Liu, Lanjuan Zhao, Yanhua He, Zhongtian Qi, Hao Ren, Hailin Tang, Ping Zhao
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
arboviruses
ixazomib
broad-spectrum antivirals screening
FDA-approved drugs
Online Access:https://www.mdpi.com/1999-4915/14/7/1381

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