A systematic pan-cancer analysis of the gasdermin (GSDM) family of genes and their correlation with prognosis, the tumor microenvironment, and drug sensitivity

A systematic pan-cancer analysis of the gasdermin (GSDM) family of genes and their correlation with prognosis, the tumor microenvironment, and drug sensitivity

Background: Pyroptosis is a programmed cell death process mediated by the gasdermin (GSDM) protein. However, limited research has been conducted to comprehensively analyze the contribution of the GSDM family in a pan-cancer setting.Methods: We systematically evaluated the gene expression, genetic va...

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Bibliographic Details
Main Authors: Yufu Zheng, Didi Yuan, Fei Zhang, Renkuan Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
pyroptosis
GSDM family
tumor microenvironment
drug sensitivity
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.926796/full

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