Granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema: a case report

Granuloma faciale (GF) is a rare benign chronic inflammatory dermatologic disease which is characterized by facial lesions. The diagnosis is mainly based on clinical and histopathology findings. It may be resistant to treatments and prone to relapse. Different treatment modalities include corticost...

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Main Authors: Abdurhman Saud Al Arfaj, Najma Khalil, Malak Alzahrani, Sufia Husain
Format: Article
Language:English
Published: PAGEPress Publications 2023-05-01
Series:Dermatology Reports
Subjects:
Online Access:https://www.pagepress.org/journals/index.php/dr/article/view/9725
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author Abdurhman Saud Al Arfaj
Najma Khalil
Malak Alzahrani
Sufia Husain
author_facet Abdurhman Saud Al Arfaj
Najma Khalil
Malak Alzahrani
Sufia Husain
author_sort Abdurhman Saud Al Arfaj
collection DOAJ
description Granuloma faciale (GF) is a rare benign chronic inflammatory dermatologic disease which is characterized by facial lesions. The diagnosis is mainly based on clinical and histopathology findings. It may be resistant to treatments and prone to relapse. Different treatment modalities include corticosteroid therapy, tacrolimus, cryotherapy and surgical methods. We report a case of GF in a patient with Remitting seronegative symmetric synovitis with pitting edema (RS3PE). A male patient with RS3PE presented with reddish brown soft nodules on and over lateral aspects of his nose and adjacent areas on his face which were diagnosed histologically as GF. He was treated with prednisolone, methotrexate and clobetasol propionate cream successfully without recurrence. To the best of our knowledge this is the first case report of GF occurring in a patient with RS3PE.
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spelling doaj.art-2a5653fce270451e97774d209bbad36d2023-05-24T17:59:01ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062023-05-0110.4081/dr.2023.9725Granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema: a case reportAbdurhman Saud Al Arfaj0Najma Khalil1Malak Alzahrani2Sufia Husain3Division of Rheumatology, Department of Medicine, College of Medicine, King Saud University, RiyadhCollege of Medicine Research Center, College of Medicine, King Saud University, RiyadhDepartment of Pathology, College of Medicine, King Saud University, RiyadhDepartment of Pathology and Laboratory Medicine, College of Medicine, King Saud University, Riyadh Granuloma faciale (GF) is a rare benign chronic inflammatory dermatologic disease which is characterized by facial lesions. The diagnosis is mainly based on clinical and histopathology findings. It may be resistant to treatments and prone to relapse. Different treatment modalities include corticosteroid therapy, tacrolimus, cryotherapy and surgical methods. We report a case of GF in a patient with Remitting seronegative symmetric synovitis with pitting edema (RS3PE). A male patient with RS3PE presented with reddish brown soft nodules on and over lateral aspects of his nose and adjacent areas on his face which were diagnosed histologically as GF. He was treated with prednisolone, methotrexate and clobetasol propionate cream successfully without recurrence. To the best of our knowledge this is the first case report of GF occurring in a patient with RS3PE. https://www.pagepress.org/journals/index.php/dr/article/view/9725granuloma facialefacial lesionshistopathologydifferential diagnosistreatment
spellingShingle Abdurhman Saud Al Arfaj
Najma Khalil
Malak Alzahrani
Sufia Husain
Granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema: a case report
Dermatology Reports
granuloma faciale
facial lesions
histopathology
differential diagnosis
treatment
title Granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema: a case report
title_full Granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema: a case report
title_fullStr Granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema: a case report
title_full_unstemmed Granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema: a case report
title_short Granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema: a case report
title_sort granuloma faciale in a patient with remitting seronegative symmetric synovitis with pitting edema a case report
topic granuloma faciale
facial lesions
histopathology
differential diagnosis
treatment
url https://www.pagepress.org/journals/index.php/dr/article/view/9725
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AT malakalzahrani granulomafacialeinapatientwithremittingseronegativesymmetricsynovitiswithpittingedemaacasereport
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