Complement Properdin Regulates the Metabolo-Inflammatory Response to a High Fat Diet

Complement Properdin Regulates the Metabolo-Inflammatory Response to a High Fat Diet

<i>Background and objectives:</i> Overnutrition leads to a metabolic and inflammatory response that includes the activation of Complement. Properdin is the only amplifier of complement activation and increases the provision of complement activation products. Its absence has previously be...

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Bibliographic Details
Main Authors: Rόisín C. Thomas, Ramiar Kheder, Hasanain Alaridhee, Naomi Martin, Cordula M. Stover
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Medicina
Subjects:
Keywords: diet
complement
mouse model
C5L2
CD36
Online Access:https://www.mdpi.com/1010-660X/56/9/484

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