Pulmonary hypertension in infants with bronchopulmonary dysplasia

An increase in the number of preterm infants and a decrease in the gestational age at birth have resulted in an increase in the number of patients with significant bronchopulmonary dysplasia (BPD) and secondary pulmonary hypertension (PH). PH contributes significantly to the high morbidity and morta...

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Main Author: Gi Beom Kim
Format: Article
Language:English
Published: Korean Pediatric Society 2010-06-01
Series:Korean Journal of Pediatrics
Subjects:
Online Access:http://kjp.or.kr/upload/pdf/kjped-53-688.pdf
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author Gi Beom Kim
author_facet Gi Beom Kim
author_sort Gi Beom Kim
collection DOAJ
description An increase in the number of preterm infants and a decrease in the gestational age at birth have resulted in an increase in the number of patients with significant bronchopulmonary dysplasia (BPD) and secondary pulmonary hypertension (PH). PH contributes significantly to the high morbidity and mortality in the BPD patients. Therefore, regular monitoring for PH by using echocardiography and B-type natriuretic peptide (BNP) or N-terminal-proBNP must be conducted in the BPD patients with greater than moderate degree to prevent PH and to ensure early treatment if PH is present. In the BPD patients with significant PH, multi-modality treatment, including treatment for correcting an underlying disease, oxygen supply, use of diverse selective pulmonary vasodilators (inhaled nitric oxide, inhaled prostacyclins, sildenafil, and endothelin-receptor antagonist) and other methods, is mandatory.
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spelling doaj.art-2a627c61ea7b47faaeded93068c962fb2022-12-22T01:44:36ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582010-06-0153668869310.3345/kjp.2010.53.6.6882010530603Pulmonary hypertension in infants with bronchopulmonary dysplasiaGi Beom Kim0Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.An increase in the number of preterm infants and a decrease in the gestational age at birth have resulted in an increase in the number of patients with significant bronchopulmonary dysplasia (BPD) and secondary pulmonary hypertension (PH). PH contributes significantly to the high morbidity and mortality in the BPD patients. Therefore, regular monitoring for PH by using echocardiography and B-type natriuretic peptide (BNP) or N-terminal-proBNP must be conducted in the BPD patients with greater than moderate degree to prevent PH and to ensure early treatment if PH is present. In the BPD patients with significant PH, multi-modality treatment, including treatment for correcting an underlying disease, oxygen supply, use of diverse selective pulmonary vasodilators (inhaled nitric oxide, inhaled prostacyclins, sildenafil, and endothelin-receptor antagonist) and other methods, is mandatory.http://kjp.or.kr/upload/pdf/kjped-53-688.pdfPulmonary hypertensionBronchopulmonary dysplasiaVasodilatorEchocardiographyBrain natriuretic peptide
spellingShingle Gi Beom Kim
Pulmonary hypertension in infants with bronchopulmonary dysplasia
Korean Journal of Pediatrics
Pulmonary hypertension
Bronchopulmonary dysplasia
Vasodilator
Echocardiography
Brain natriuretic peptide
title Pulmonary hypertension in infants with bronchopulmonary dysplasia
title_full Pulmonary hypertension in infants with bronchopulmonary dysplasia
title_fullStr Pulmonary hypertension in infants with bronchopulmonary dysplasia
title_full_unstemmed Pulmonary hypertension in infants with bronchopulmonary dysplasia
title_short Pulmonary hypertension in infants with bronchopulmonary dysplasia
title_sort pulmonary hypertension in infants with bronchopulmonary dysplasia
topic Pulmonary hypertension
Bronchopulmonary dysplasia
Vasodilator
Echocardiography
Brain natriuretic peptide
url http://kjp.or.kr/upload/pdf/kjped-53-688.pdf
work_keys_str_mv AT gibeomkim pulmonaryhypertensionininfantswithbronchopulmonarydysplasia