RelB+ Steady-State Migratory Dendritic Cells Control the Peripheral Pool of the Natural Foxp3+ Regulatory T Cells

RelB+ Steady-State Migratory Dendritic Cells Control the Peripheral Pool of the Natural Foxp3+ Regulatory T Cells

Thymus-derived natural Foxp3+ CD4+ regulatory T cells (nTregs) play a key role in maintaining immune tolerance and preventing autoimmune disease. Several studies indicate that dendritic cells (DCs) are critically involved in the maintenance and proliferation of nTregs. However, the mechanisms how DC...

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Bibliografski detalji
Glavni autori: Anja Döhler, Theresa Schneider, Ina Eckert, Eliana Ribechini, Nico Andreas, Marc Riemann, Boris Reizis, Falk Weih, Manfred B. Lutz
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2017-06-01
Serija:Frontiers in Immunology
Teme:
dendritic cells
RelB
regulatory T cells
IL-2
lymph nodes
Online pristup:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00726/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00726/full

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