Integrin molecular tension required for focal adhesion maturation and YAP nuclear translocation

Focal adhesions (FAs) provide the cells linkages to extracellular matrix (ECM) at sites of integrins binding and transmit mechanical forces between the ECM and the actin cytoskeleton. Cells sense and respond to physical stimuli from their surrounding environment through the activation of mechanosens...

Full description

Bibliographic Details
Main Authors: Cheng-Yu Chang Chien, Shih-Hua Chou, Hsiao-Hui Lee
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822000875