Potential of ethosomes for enhanced transdermal drug delivery in skin diseases
Ethosomes are novel ethanolic phospholipid vesicles which are significantly used for the transdermal drug delivery. Ethanol is an efficient permeation enhancer which is used in ethosomes about 20-45%. These are non-invasive in nature and have emerged as an area of active research interest because th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2022-10-01
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| Series: | Nanomedicine Journal |
| Subjects: | |
| Online Access: | https://nmj.mums.ac.ir/article_20926_c674807c36159924a179f194c46d3aae.pdf |
| _version_ | 1811247878706823168 |
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| author | Bhumika Kumar Pravat Sahoo |
| author_facet | Bhumika Kumar Pravat Sahoo |
| author_sort | Bhumika Kumar |
| collection | DOAJ |
| description | Ethosomes are novel ethanolic phospholipid vesicles which are significantly used for the transdermal drug delivery. Ethanol is an efficient permeation enhancer which is used in ethosomes about 20-45%. These are non-invasive in nature and have emerged as an area of active research interest because they significantly lead to enhanced skin penetration, improvement in drug delivery, increased drug entrapment efficiency it can deliver both hydrophilic and lipophilic drugs efficiently. Increased patient compliance etc. The drug penetrates the skin surface and gets absorbed by two phases i.e., the ethanol effect and ethosomes effect. Ethosomes are predominantly being used over liposomes because of their greater penetration rate which is attributed to the high concentration of ethanol. Hence it is an active area of research. The primary aim of the review is to provide a comprehensive account on the methods of preparation, properties, characterization, advantages and applications of ethosomes in the management of several skin diseases. |
| first_indexed | 2024-04-12T15:17:14Z |
| format | Article |
| id | doaj.art-2a6ca021f37745fdb32d4c73bab73f61 |
| institution | Directory Open Access Journal |
| issn | 2322-3049 2322-5904 |
| language | English |
| last_indexed | 2024-04-12T15:17:14Z |
| publishDate | 2022-10-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Nanomedicine Journal |
| spelling | doaj.art-2a6ca021f37745fdb32d4c73bab73f612022-12-22T03:27:35ZengMashhad University of Medical SciencesNanomedicine Journal2322-30492322-59042022-10-019427328010.22038/nmj.2022.66753.170320926Potential of ethosomes for enhanced transdermal drug delivery in skin diseasesBhumika Kumar0Pravat Sahoo1Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University (DPSRU) Pushp Vihar Sector III, MB Road, New Delhi- 110017 (INDIA) New DelhiDepartment of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University (DPSRU) Pushp Vihar Sector III, MB Road, New Delhi- 110017 (INDIA) New DelhiEthosomes are novel ethanolic phospholipid vesicles which are significantly used for the transdermal drug delivery. Ethanol is an efficient permeation enhancer which is used in ethosomes about 20-45%. These are non-invasive in nature and have emerged as an area of active research interest because they significantly lead to enhanced skin penetration, improvement in drug delivery, increased drug entrapment efficiency it can deliver both hydrophilic and lipophilic drugs efficiently. Increased patient compliance etc. The drug penetrates the skin surface and gets absorbed by two phases i.e., the ethanol effect and ethosomes effect. Ethosomes are predominantly being used over liposomes because of their greater penetration rate which is attributed to the high concentration of ethanol. Hence it is an active area of research. The primary aim of the review is to provide a comprehensive account on the methods of preparation, properties, characterization, advantages and applications of ethosomes in the management of several skin diseases.https://nmj.mums.ac.ir/article_20926_c674807c36159924a179f194c46d3aae.pdfethanolethosomestransdermal drug delivery systempermeation enhancers |
| spellingShingle | Bhumika Kumar Pravat Sahoo Potential of ethosomes for enhanced transdermal drug delivery in skin diseases Nanomedicine Journal ethanol ethosomes transdermal drug delivery system permeation enhancers |
| title | Potential of ethosomes for enhanced transdermal drug delivery in skin diseases |
| title_full | Potential of ethosomes for enhanced transdermal drug delivery in skin diseases |
| title_fullStr | Potential of ethosomes for enhanced transdermal drug delivery in skin diseases |
| title_full_unstemmed | Potential of ethosomes for enhanced transdermal drug delivery in skin diseases |
| title_short | Potential of ethosomes for enhanced transdermal drug delivery in skin diseases |
| title_sort | potential of ethosomes for enhanced transdermal drug delivery in skin diseases |
| topic | ethanol ethosomes transdermal drug delivery system permeation enhancers |
| url | https://nmj.mums.ac.ir/article_20926_c674807c36159924a179f194c46d3aae.pdf |
| work_keys_str_mv | AT bhumikakumar potentialofethosomesforenhancedtransdermaldrugdeliveryinskindiseases AT pravatsahoo potentialofethosomesforenhancedtransdermaldrugdeliveryinskindiseases |