Trends in cancer incidence in Maputo, Mozambique, 1991-2008.
Very limited information is available regarding the incidence of cancer in sub-Saharan Africa. We analyzed changes in cancer patterns from 1991 to 2008 in Maputo (Mozambique).We calculated the rates of incidence of different cancer sites by sex in the 5-year age-group of the population of Maputo cit...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4481529?pdf=render |
| _version_ | 1831567755214585856 |
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| author | Cesaltina Lorenzoni Alba Vilajeliu Carla Carrilho Mamudo R Ismail Paola Castillo Orvalho Augusto Alberto L García-Basteiro Mohsin Sidat Silvia de Sanjosé Clara Menéndez Jaume Ordi |
| author_facet | Cesaltina Lorenzoni Alba Vilajeliu Carla Carrilho Mamudo R Ismail Paola Castillo Orvalho Augusto Alberto L García-Basteiro Mohsin Sidat Silvia de Sanjosé Clara Menéndez Jaume Ordi |
| author_sort | Cesaltina Lorenzoni |
| collection | DOAJ |
| description | Very limited information is available regarding the incidence of cancer in sub-Saharan Africa. We analyzed changes in cancer patterns from 1991 to 2008 in Maputo (Mozambique).We calculated the rates of incidence of different cancer sites by sex in the 5-year age-group of the population of Maputo city as well as age-standardized rates (ASRs) and average annual percentage changes (AAPC).Over the 18-year study period a total of 12,674 cases of cancer (56.9% females) were registered with an overall increase in the risk of cancer in both sexes. In males, the most common cancers were those of the prostate, Kaposi sarcoma (KS) and the liver. Prostate cancer showed the most dramatic increase over the whole study period (AAPC +11.3%; 95% CI: 9.7-13.0), with an ASR of 61.7 per 105 in 2003-2008. In females, the most frequent cancers were of the uterine cervix, the breast and KS, with the former increasing along the whole study period (AAPC + 4.7%; 95% CI: 3.4-6) with an ASR of 62.0 per 105 in 2003-2008 as well as breast cancer (AAPC +6.5%; 95%CI: 4.3-8.7).Overall, the risk of cancer rose in both sexes during the study period, particularly among cancers associated with westernization of lifestyles (prostate, breast), combined with increasingly rising incidences or limited changes in cancers associated with infection and poverty (uterine cervix, liver). Moreover, the burden of AIDS-associated cancers has shown a marked increase. |
| first_indexed | 2024-12-17T12:03:12Z |
| format | Article |
| id | doaj.art-2a77ef3da04b40f8a1cd75a3a9b1b3b8 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-17T12:03:12Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-2a77ef3da04b40f8a1cd75a3a9b1b3b82022-12-21T21:49:44ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01106e013046910.1371/journal.pone.0130469Trends in cancer incidence in Maputo, Mozambique, 1991-2008.Cesaltina LorenzoniAlba VilajeliuCarla CarrilhoMamudo R IsmailPaola CastilloOrvalho AugustoAlberto L García-BasteiroMohsin SidatSilvia de SanjoséClara MenéndezJaume OrdiVery limited information is available regarding the incidence of cancer in sub-Saharan Africa. We analyzed changes in cancer patterns from 1991 to 2008 in Maputo (Mozambique).We calculated the rates of incidence of different cancer sites by sex in the 5-year age-group of the population of Maputo city as well as age-standardized rates (ASRs) and average annual percentage changes (AAPC).Over the 18-year study period a total of 12,674 cases of cancer (56.9% females) were registered with an overall increase in the risk of cancer in both sexes. In males, the most common cancers were those of the prostate, Kaposi sarcoma (KS) and the liver. Prostate cancer showed the most dramatic increase over the whole study period (AAPC +11.3%; 95% CI: 9.7-13.0), with an ASR of 61.7 per 105 in 2003-2008. In females, the most frequent cancers were of the uterine cervix, the breast and KS, with the former increasing along the whole study period (AAPC + 4.7%; 95% CI: 3.4-6) with an ASR of 62.0 per 105 in 2003-2008 as well as breast cancer (AAPC +6.5%; 95%CI: 4.3-8.7).Overall, the risk of cancer rose in both sexes during the study period, particularly among cancers associated with westernization of lifestyles (prostate, breast), combined with increasingly rising incidences or limited changes in cancers associated with infection and poverty (uterine cervix, liver). Moreover, the burden of AIDS-associated cancers has shown a marked increase.http://europepmc.org/articles/PMC4481529?pdf=render |
| spellingShingle | Cesaltina Lorenzoni Alba Vilajeliu Carla Carrilho Mamudo R Ismail Paola Castillo Orvalho Augusto Alberto L García-Basteiro Mohsin Sidat Silvia de Sanjosé Clara Menéndez Jaume Ordi Trends in cancer incidence in Maputo, Mozambique, 1991-2008. PLoS ONE |
| title | Trends in cancer incidence in Maputo, Mozambique, 1991-2008. |
| title_full | Trends in cancer incidence in Maputo, Mozambique, 1991-2008. |
| title_fullStr | Trends in cancer incidence in Maputo, Mozambique, 1991-2008. |
| title_full_unstemmed | Trends in cancer incidence in Maputo, Mozambique, 1991-2008. |
| title_short | Trends in cancer incidence in Maputo, Mozambique, 1991-2008. |
| title_sort | trends in cancer incidence in maputo mozambique 1991 2008 |
| url | http://europepmc.org/articles/PMC4481529?pdf=render |
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