Minimally Invasive Glaucoma Surgery: A Review of the Literature

Minimally invasive glaucoma surgery (MIGS) has emerged as a novel approach in the glaucoma treatment spectrum, offering a range of diverse procedures and devices aimed at reducing intraocular pressure (IOP). MIGS can be broadly classified into several categories: those that enhance trabecular outflo...

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Main Authors: Michael Balas, David J. Mathew
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Vision
Subjects:
Online Access:https://www.mdpi.com/2411-5150/7/3/54
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author Michael Balas
David J. Mathew
author_facet Michael Balas
David J. Mathew
author_sort Michael Balas
collection DOAJ
description Minimally invasive glaucoma surgery (MIGS) has emerged as a novel approach in the glaucoma treatment spectrum, offering a range of diverse procedures and devices aimed at reducing intraocular pressure (IOP). MIGS can be broadly classified into several categories: those that enhance trabecular outflow (Trabectome, iStent, Hydrus Microstent, Kahook Dual Blade, high frequency deep sclerotomy, and gonioscopy-assisted transluminal trabeculotomy), those that augment suprachoroidal outflow (CyPass Microstent and iStent Supra), those that target Schlemm’s canal (TRAB360 and the OMNI Surgical System, Streamline, and Ab Interno Canaloplasty), and conjunctival bleb-forming procedures (EX-PRESS Glaucoma Filtration Device, Xen Gel Stent and PreserFlo MicroShunt). MIGS is considered to have a shorter surgical time and fewer severe complications when compared to traditional glaucoma surgeries such as trabeculectomy and glaucoma drainage device implantation (Ahmed, Baerveldt, and Molteno valves). This literature review comprehensively examines the distinct MIGS devices and procedures, their underlying mechanisms, and clinical outcomes, emphasizing the importance of evaluating the efficacy and complications of each approach individually. As the field of MIGS continues to evolve, it is crucial to prioritize high-quality, long-term studies to better understand the safety and effectiveness of these innovative interventions in glaucoma management.
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spelling doaj.art-2a78e12ea2e04b98a4ae63f1fd33736e2023-11-19T13:24:26ZengMDPI AGVision2411-51502023-08-01735410.3390/vision7030054Minimally Invasive Glaucoma Surgery: A Review of the LiteratureMichael Balas0David J. Mathew1Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, CanadaDonald K. Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, ON M5T 0S8, CanadaMinimally invasive glaucoma surgery (MIGS) has emerged as a novel approach in the glaucoma treatment spectrum, offering a range of diverse procedures and devices aimed at reducing intraocular pressure (IOP). MIGS can be broadly classified into several categories: those that enhance trabecular outflow (Trabectome, iStent, Hydrus Microstent, Kahook Dual Blade, high frequency deep sclerotomy, and gonioscopy-assisted transluminal trabeculotomy), those that augment suprachoroidal outflow (CyPass Microstent and iStent Supra), those that target Schlemm’s canal (TRAB360 and the OMNI Surgical System, Streamline, and Ab Interno Canaloplasty), and conjunctival bleb-forming procedures (EX-PRESS Glaucoma Filtration Device, Xen Gel Stent and PreserFlo MicroShunt). MIGS is considered to have a shorter surgical time and fewer severe complications when compared to traditional glaucoma surgeries such as trabeculectomy and glaucoma drainage device implantation (Ahmed, Baerveldt, and Molteno valves). This literature review comprehensively examines the distinct MIGS devices and procedures, their underlying mechanisms, and clinical outcomes, emphasizing the importance of evaluating the efficacy and complications of each approach individually. As the field of MIGS continues to evolve, it is crucial to prioritize high-quality, long-term studies to better understand the safety and effectiveness of these innovative interventions in glaucoma management.https://www.mdpi.com/2411-5150/7/3/54minimally invasive glaucoma surgeryMIGSglaucomaintraocular pressuretrabecular outflowsuprachoroidal outflow
spellingShingle Michael Balas
David J. Mathew
Minimally Invasive Glaucoma Surgery: A Review of the Literature
Vision
minimally invasive glaucoma surgery
MIGS
glaucoma
intraocular pressure
trabecular outflow
suprachoroidal outflow
title Minimally Invasive Glaucoma Surgery: A Review of the Literature
title_full Minimally Invasive Glaucoma Surgery: A Review of the Literature
title_fullStr Minimally Invasive Glaucoma Surgery: A Review of the Literature
title_full_unstemmed Minimally Invasive Glaucoma Surgery: A Review of the Literature
title_short Minimally Invasive Glaucoma Surgery: A Review of the Literature
title_sort minimally invasive glaucoma surgery a review of the literature
topic minimally invasive glaucoma surgery
MIGS
glaucoma
intraocular pressure
trabecular outflow
suprachoroidal outflow
url https://www.mdpi.com/2411-5150/7/3/54
work_keys_str_mv AT michaelbalas minimallyinvasiveglaucomasurgeryareviewoftheliterature
AT davidjmathew minimallyinvasiveglaucomasurgeryareviewoftheliterature