Half-Fan-Based Intensity-Weighted Region-of-Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation Therapy
ObjectivesWith the increased use of computed tomography (CT) in clinics, dose reduction is the most important feature people seek when considering new CT techniques or applications. We developed an intensity-weighted region-of-interest (IWROI) imaging method in an exact half-fan geometry to reduce t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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The Korean Society of Medical Informatics
2016-10-01
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| Series: | Healthcare Informatics Research |
| Subjects: | |
| Online Access: | http://e-hir.org/upload/pdf/hir-22-316.pdf |
| _version_ | 1819000054208266240 |
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| author | Boyeol Yoo Kihong Son Rizza Pua Jinsung Kim Alexander Solodov Seungryong Cho |
| author_facet | Boyeol Yoo Kihong Son Rizza Pua Jinsung Kim Alexander Solodov Seungryong Cho |
| author_sort | Boyeol Yoo |
| collection | DOAJ |
| description | ObjectivesWith the increased use of computed tomography (CT) in clinics, dose reduction is the most important feature people seek when considering new CT techniques or applications. We developed an intensity-weighted region-of-interest (IWROI) imaging method in an exact half-fan geometry to reduce the imaging radiation dose to patients in cone-beam CT (CBCT) for image-guided radiation therapy (IGRT). While dose reduction is highly desirable, preserving the high-quality images of the ROI is also important for target localization in IGRT.MethodsAn intensity-weighting (IW) filter made of copper was mounted in place of a bowtie filter on the X-ray tube unit of an on-board imager (OBI) system such that the filter can substantially reduce radiation exposure to the outer ROI. In addition to mounting the IW filter, the lead-blade collimation of the OBI was adjusted to produce an exact half-fan scanning geometry for a further reduction of the radiation dose. The chord-based rebinned backprojection-filtration (BPF) algorithm in circular CBCT was implemented for image reconstruction, and a humanoid pelvis phantom was used for the IWROI imaging experiment.ResultsThe IWROI image of the phantom was successfully reconstructed after beam-quality correction, and it was registered to the reference image within an acceptable level of tolerance. Dosimetric measurements revealed that the dose is reduced by approximately 61% in the inner ROI and by 73% in the outer ROI compared to the conventional bowtie filter-based half-fan scan.ConclusionsThe IWROI method substantially reduces the imaging radiation dose and provides reconstructed images with an acceptable level of quality for patient setup and target localization. The proposed half-fan-based IWROI imaging technique can add a valuable option to CBCT in IGRT applications. |
| first_indexed | 2024-12-20T22:27:13Z |
| format | Article |
| id | doaj.art-2a800eaa72c14982972da4ded9e5fbdd |
| institution | Directory Open Access Journal |
| issn | 2093-3681 2093-369X |
| language | English |
| last_indexed | 2024-12-20T22:27:13Z |
| publishDate | 2016-10-01 |
| publisher | The Korean Society of Medical Informatics |
| record_format | Article |
| series | Healthcare Informatics Research |
| spelling | doaj.art-2a800eaa72c14982972da4ded9e5fbdd2022-12-21T19:24:47ZengThe Korean Society of Medical InformaticsHealthcare Informatics Research2093-36812093-369X2016-10-0122431632510.4258/hir.2016.22.4.316824Half-Fan-Based Intensity-Weighted Region-of-Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation TherapyBoyeol Yoo0Kihong Son1Rizza Pua2Jinsung Kim3Alexander Solodov4Seungryong Cho5Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea.Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea.Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea.Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea.Department of Nuclear Engineering, Khalifa University, Abu Dhabi, UAE.Department of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea.ObjectivesWith the increased use of computed tomography (CT) in clinics, dose reduction is the most important feature people seek when considering new CT techniques or applications. We developed an intensity-weighted region-of-interest (IWROI) imaging method in an exact half-fan geometry to reduce the imaging radiation dose to patients in cone-beam CT (CBCT) for image-guided radiation therapy (IGRT). While dose reduction is highly desirable, preserving the high-quality images of the ROI is also important for target localization in IGRT.MethodsAn intensity-weighting (IW) filter made of copper was mounted in place of a bowtie filter on the X-ray tube unit of an on-board imager (OBI) system such that the filter can substantially reduce radiation exposure to the outer ROI. In addition to mounting the IW filter, the lead-blade collimation of the OBI was adjusted to produce an exact half-fan scanning geometry for a further reduction of the radiation dose. The chord-based rebinned backprojection-filtration (BPF) algorithm in circular CBCT was implemented for image reconstruction, and a humanoid pelvis phantom was used for the IWROI imaging experiment.ResultsThe IWROI image of the phantom was successfully reconstructed after beam-quality correction, and it was registered to the reference image within an acceptable level of tolerance. Dosimetric measurements revealed that the dose is reduced by approximately 61% in the inner ROI and by 73% in the outer ROI compared to the conventional bowtie filter-based half-fan scan.ConclusionsThe IWROI method substantially reduces the imaging radiation dose and provides reconstructed images with an acceptable level of quality for patient setup and target localization. The proposed half-fan-based IWROI imaging technique can add a valuable option to CBCT in IGRT applications.http://e-hir.org/upload/pdf/hir-22-316.pdfcone-beam computed tomographylow-doseregion-of-interesthalf-fanimage-guided radiation therapy |
| spellingShingle | Boyeol Yoo Kihong Son Rizza Pua Jinsung Kim Alexander Solodov Seungryong Cho Half-Fan-Based Intensity-Weighted Region-of-Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation Therapy Healthcare Informatics Research cone-beam computed tomography low-dose region-of-interest half-fan image-guided radiation therapy |
| title | Half-Fan-Based Intensity-Weighted Region-of-Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation Therapy |
| title_full | Half-Fan-Based Intensity-Weighted Region-of-Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation Therapy |
| title_fullStr | Half-Fan-Based Intensity-Weighted Region-of-Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation Therapy |
| title_full_unstemmed | Half-Fan-Based Intensity-Weighted Region-of-Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation Therapy |
| title_short | Half-Fan-Based Intensity-Weighted Region-of-Interest Imaging for Low-Dose Cone-Beam CT in Image-Guided Radiation Therapy |
| title_sort | half fan based intensity weighted region of interest imaging for low dose cone beam ct in image guided radiation therapy |
| topic | cone-beam computed tomography low-dose region-of-interest half-fan image-guided radiation therapy |
| url | http://e-hir.org/upload/pdf/hir-22-316.pdf |
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