Sonochemical degradation of azithromycin in aqueous solution

Background: The presence of pharmaceutical substances and their residual in water resources is an important environmental concern. Azithromycin, an antibiotic that is used for the treatment of infectious diseases, is a pollutant agent in the wastewater. The aim of this study was to investigate az...

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Main Author: Atiyeh Yazdani1, Mohammad Hossein Sayadi1*
Format: Article
Language:English
Published: Kerman University of Medical Sciences 2018-05-01
Series:Environmental Health Engineering and Management
Online Access:http://ehemj.com/article-1-342-en.html
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author Atiyeh Yazdani1, Mohammad Hossein Sayadi1*
author_facet Atiyeh Yazdani1, Mohammad Hossein Sayadi1*
author_sort Atiyeh Yazdani1, Mohammad Hossein Sayadi1*
collection DOAJ
description Background: The presence of pharmaceutical substances and their residual in water resources is an important environmental concern. Azithromycin, an antibiotic that is used for the treatment of infectious diseases, is a pollutant agent in the wastewater. The aim of this study was to investigate azithromycin degradation in aqueous solution through ultrasonic process in the presence of zinc oxide nanoparticles as catalysts. Methods: Sonocatalytic experiments were performed at variable conditions including pH (3- 8), temperature (20-60°C), time (3-21 minutes), catalyst dosage (0.25-2 g/L), hydrogen peroxide concentration (15-100 mg/L) and initial azithromycin concentration (10-100 mg/L). Results: The optimum values for pH (3), temperature (40°C), time (15 minutes), catalyst dosage (1 g/L), H2O2 concentration (50 mg/L) and initial azithromycin concentration (20 mg/L) were determined. The highest degradation efficiency of 98.4% was achieved after 15 minutes of ultrasonic irradiation under optimum condition. Conclusion: According to the results, ultrasonic irradiation is able to degrade azithromycin. In addition, ZnO and hydroxyl radical can successfully accelerate the reaction process in the shortest possible time.
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spelling doaj.art-2a80242d987845d89288e5f24df14f912022-12-21T17:31:35ZengKerman University of Medical SciencesEnvironmental Health Engineering and Management2423-37652423-43112018-05-0152859210.15171/EHEM.2018.13Sonochemical degradation of azithromycin in aqueous solutionAtiyeh Yazdani1, Mohammad Hossein Sayadi1*Background: The presence of pharmaceutical substances and their residual in water resources is an important environmental concern. Azithromycin, an antibiotic that is used for the treatment of infectious diseases, is a pollutant agent in the wastewater. The aim of this study was to investigate azithromycin degradation in aqueous solution through ultrasonic process in the presence of zinc oxide nanoparticles as catalysts. Methods: Sonocatalytic experiments were performed at variable conditions including pH (3- 8), temperature (20-60°C), time (3-21 minutes), catalyst dosage (0.25-2 g/L), hydrogen peroxide concentration (15-100 mg/L) and initial azithromycin concentration (10-100 mg/L). Results: The optimum values for pH (3), temperature (40°C), time (15 minutes), catalyst dosage (1 g/L), H2O2 concentration (50 mg/L) and initial azithromycin concentration (20 mg/L) were determined. The highest degradation efficiency of 98.4% was achieved after 15 minutes of ultrasonic irradiation under optimum condition. Conclusion: According to the results, ultrasonic irradiation is able to degrade azithromycin. In addition, ZnO and hydroxyl radical can successfully accelerate the reaction process in the shortest possible time.http://ehemj.com/article-1-342-en.html
spellingShingle Atiyeh Yazdani1, Mohammad Hossein Sayadi1*
Sonochemical degradation of azithromycin in aqueous solution
Environmental Health Engineering and Management
title Sonochemical degradation of azithromycin in aqueous solution
title_full Sonochemical degradation of azithromycin in aqueous solution
title_fullStr Sonochemical degradation of azithromycin in aqueous solution
title_full_unstemmed Sonochemical degradation of azithromycin in aqueous solution
title_short Sonochemical degradation of azithromycin in aqueous solution
title_sort sonochemical degradation of azithromycin in aqueous solution
url http://ehemj.com/article-1-342-en.html
work_keys_str_mv AT atiyehyazdani1mohammadhosseinsayadi1 sonochemicaldegradationofazithromycininaqueoussolution