Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants

Rui Wang et al. report a comprehensive analysis of nearly 13,000 SARS-CoV-2 genome sequences isolated from patients in the United States, comprising more than 7000 single mutations. They show that SARS-CoV-2 genomes cluster into four distinct groups and that two of these groups are potentially more...

Full description

Bibliographic Details
Main Authors: Rui Wang, Jiahui Chen, Kaifu Gao, Yuta Hozumi, Changchuan Yin, Guo-Wei Wei
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01754-6
_version_ 1818982326044983296
author Rui Wang
Jiahui Chen
Kaifu Gao
Yuta Hozumi
Changchuan Yin
Guo-Wei Wei
author_facet Rui Wang
Jiahui Chen
Kaifu Gao
Yuta Hozumi
Changchuan Yin
Guo-Wei Wei
author_sort Rui Wang
collection DOAJ
description Rui Wang et al. report a comprehensive analysis of nearly 13,000 SARS-CoV-2 genome sequences isolated from patients in the United States, comprising more than 7000 single mutations. They show that SARS-CoV-2 genomes cluster into four distinct groups and that two of these groups are potentially more infectious, underlining the urgent need for viral control strategies in the US.
first_indexed 2024-12-20T17:45:26Z
format Article
id doaj.art-2a818f9a3ddf40a5a4452848ad4f6e71
institution Directory Open Access Journal
issn 2399-3642
language English
last_indexed 2024-12-20T17:45:26Z
publishDate 2021-02-01
publisher Nature Portfolio
record_format Article
series Communications Biology
spelling doaj.art-2a818f9a3ddf40a5a4452848ad4f6e712022-12-21T19:30:58ZengNature PortfolioCommunications Biology2399-36422021-02-014111410.1038/s42003-021-01754-6Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variantsRui Wang0Jiahui Chen1Kaifu Gao2Yuta Hozumi3Changchuan Yin4Guo-Wei Wei5Department of Mathematics, Michigan State UniversityDepartment of Mathematics, Michigan State UniversityDepartment of Mathematics, Michigan State UniversityDepartment of Mathematics, Michigan State UniversityDepartment of Mathematics, Statistics, and Computer Science, University of Illinois at ChicagoDepartment of Mathematics, Michigan State UniversityRui Wang et al. report a comprehensive analysis of nearly 13,000 SARS-CoV-2 genome sequences isolated from patients in the United States, comprising more than 7000 single mutations. They show that SARS-CoV-2 genomes cluster into four distinct groups and that two of these groups are potentially more infectious, underlining the urgent need for viral control strategies in the US.https://doi.org/10.1038/s42003-021-01754-6
spellingShingle Rui Wang
Jiahui Chen
Kaifu Gao
Yuta Hozumi
Changchuan Yin
Guo-Wei Wei
Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants
Communications Biology
title Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants
title_full Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants
title_fullStr Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants
title_full_unstemmed Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants
title_short Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants
title_sort analysis of sars cov 2 mutations in the united states suggests presence of four substrains and novel variants
url https://doi.org/10.1038/s42003-021-01754-6
work_keys_str_mv AT ruiwang analysisofsarscov2mutationsintheunitedstatessuggestspresenceoffoursubstrainsandnovelvariants
AT jiahuichen analysisofsarscov2mutationsintheunitedstatessuggestspresenceoffoursubstrainsandnovelvariants
AT kaifugao analysisofsarscov2mutationsintheunitedstatessuggestspresenceoffoursubstrainsandnovelvariants
AT yutahozumi analysisofsarscov2mutationsintheunitedstatessuggestspresenceoffoursubstrainsandnovelvariants
AT changchuanyin analysisofsarscov2mutationsintheunitedstatessuggestspresenceoffoursubstrainsandnovelvariants
AT guoweiwei analysisofsarscov2mutationsintheunitedstatessuggestspresenceoffoursubstrainsandnovelvariants