Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries?
By 2030, 70% of cancers will occur in developing countries. Head and neck cancers are primarily a developing world disease. While anatomical location and the extent of cancers are central to defining prognosis and staging, the American Joint Committee on Cancer (AJCC)/International Union Against Can...
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| Format: | Article |
| Language: | English |
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Wiley
2020-07-01
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| Series: | OTO Open |
| Online Access: | https://doi.org/10.1177/2473974X20938313 |
| _version_ | 1797425180383903744 |
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| author | Johannes J. Fagan MBChB, MMed, FCS Julie Wetter MBChB, MMed, FCRadOnc Jeffrey Otiti MBCHB, MMed Joyce Aswani MBChB, MMed Anna Konney MD, FWACS, FGCPS Evelyne Diom Kenneth Baidoo MD, FWACS, FGCS Paul Onakoya MBBS Rajab Mugabo MMed Patrick Noah MBBS, FCS Victor Mashamba MD, MMed Innocent Kundiona MBChB, MMed Chege Macharia MBChB, FCS Mohammed Garba Mainasara MBBS, PGDM, FWACS Melesse Gebeyehu MD Mesele Bogale MD Khaled Twier MMed, FCS Marco Faniriko MD, FCS Getachew Beza Melesse MD Mark G. Shrime MD, PhD, MPH |
| author_facet | Johannes J. Fagan MBChB, MMed, FCS Julie Wetter MBChB, MMed, FCRadOnc Jeffrey Otiti MBCHB, MMed Joyce Aswani MBChB, MMed Anna Konney MD, FWACS, FGCPS Evelyne Diom Kenneth Baidoo MD, FWACS, FGCS Paul Onakoya MBBS Rajab Mugabo MMed Patrick Noah MBBS, FCS Victor Mashamba MD, MMed Innocent Kundiona MBChB, MMed Chege Macharia MBChB, FCS Mohammed Garba Mainasara MBBS, PGDM, FWACS Melesse Gebeyehu MD Mesele Bogale MD Khaled Twier MMed, FCS Marco Faniriko MD, FCS Getachew Beza Melesse MD Mark G. Shrime MD, PhD, MPH |
| author_sort | Johannes J. Fagan MBChB, MMed, FCS |
| collection | DOAJ |
| description | By 2030, 70% of cancers will occur in developing countries. Head and neck cancers are primarily a developing world disease. While anatomical location and the extent of cancers are central to defining prognosis and staging, the American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) have incorporated nonanatomic factors that correlate with prognosis into staging (eg, p16 status of oropharyngeal cancers). However, 16 of 17 head and neck surgeons from 13 African countries cannot routinely test for p16 status and hence can no longer apply AJCC/UICC staging to oropharyngeal cancer. While the AJCC/UICC should continue to refine staging that best reflects treatment outcomes and prognosis by incorporating new nonanatomical factors, they should also retain and refine anatomically based staging to serve the needs of clinicians and their patients in resource-constrained settings. Not to do so would diminish their global relevance and in so doing also disadvantage most of the world’s cancer patients. |
| first_indexed | 2024-03-09T08:12:20Z |
| format | Article |
| id | doaj.art-2a8ece41acd54e2c9d3a7002235b6b8b |
| institution | Directory Open Access Journal |
| issn | 2473-974X |
| language | English |
| last_indexed | 2024-03-09T08:12:20Z |
| publishDate | 2020-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | OTO Open |
| spelling | doaj.art-2a8ece41acd54e2c9d3a7002235b6b8b2023-12-02T23:07:05ZengWileyOTO Open2473-974X2020-07-01410.1177/2473974X20938313Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries?Johannes J. Fagan MBChB, MMed, FCS0Julie Wetter MBChB, MMed, FCRadOnc1Jeffrey Otiti MBCHB, MMed2Joyce Aswani MBChB, MMed3Anna Konney MD, FWACS, FGCPS4Evelyne Diom5Kenneth Baidoo MD, FWACS, FGCS6Paul Onakoya MBBS7Rajab Mugabo MMed8Patrick Noah MBBS, FCS9Victor Mashamba MD, MMed10Innocent Kundiona MBChB, MMed11Chege Macharia MBChB, FCS12Mohammed Garba Mainasara MBBS, PGDM, FWACS13Melesse Gebeyehu MD14Mesele Bogale MD15Khaled Twier MMed, FCS16Marco Faniriko MD, FCS17Getachew Beza Melesse MD18Mark G. Shrime MD, PhD, MPH19Division of Otolaryngology, University of Cape Town, South AfricaDepartment Radiation Oncology, Groote Schuur Hospital, University of Cape Town, Cape Town, South AfricaUganda Cancer Institute, Kampala, UgandaDepartment of Surgery, College of Health Sciences, University of Nairobi, Nairobi, KenyaENT Department, Komfo Anokye Teaching Hospital, Kumasi, GhanaDivision of Otolaryngology, Hôpital de la Paix, Universite Assane Seck, Ziguinchor, SenegalKorle Bu Teaching Hospital, Accra, GhanaUniversity of Ibadan/University College Hospital, Ibadan, NigeriaThe Aga Khan Hospital, Dar es Salaam, TanzaniaCollege of Medicine, Blantyre, MalawiMuhimbili National Hospital, Dar Es Salaam, TanzaniaHarare, ZimbabweAIC Kijabe Hospital, KenyaNational Ear Care Centre Kaduna Nigeria, Kaduna, NigeriaBahir dar University, EthiopiaAdama General Hospital, Adam, EthiopiaOshakati, Namibia and LibyaLutheran Hospital Salfa Sambava, MadagascarHawassa University Referral Hospital, Hawassa, EthiopiaProgram in Global Surgery and Social Change, Harvard Medical School and Center for Global Surgery Evaluation, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USABy 2030, 70% of cancers will occur in developing countries. Head and neck cancers are primarily a developing world disease. While anatomical location and the extent of cancers are central to defining prognosis and staging, the American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) have incorporated nonanatomic factors that correlate with prognosis into staging (eg, p16 status of oropharyngeal cancers). However, 16 of 17 head and neck surgeons from 13 African countries cannot routinely test for p16 status and hence can no longer apply AJCC/UICC staging to oropharyngeal cancer. While the AJCC/UICC should continue to refine staging that best reflects treatment outcomes and prognosis by incorporating new nonanatomical factors, they should also retain and refine anatomically based staging to serve the needs of clinicians and their patients in resource-constrained settings. Not to do so would diminish their global relevance and in so doing also disadvantage most of the world’s cancer patients.https://doi.org/10.1177/2473974X20938313 |
| spellingShingle | Johannes J. Fagan MBChB, MMed, FCS Julie Wetter MBChB, MMed, FCRadOnc Jeffrey Otiti MBCHB, MMed Joyce Aswani MBChB, MMed Anna Konney MD, FWACS, FGCPS Evelyne Diom Kenneth Baidoo MD, FWACS, FGCS Paul Onakoya MBBS Rajab Mugabo MMed Patrick Noah MBBS, FCS Victor Mashamba MD, MMed Innocent Kundiona MBChB, MMed Chege Macharia MBChB, FCS Mohammed Garba Mainasara MBBS, PGDM, FWACS Melesse Gebeyehu MD Mesele Bogale MD Khaled Twier MMed, FCS Marco Faniriko MD, FCS Getachew Beza Melesse MD Mark G. Shrime MD, PhD, MPH Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries? OTO Open |
| title | Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries? |
| title_full | Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries? |
| title_fullStr | Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries? |
| title_full_unstemmed | Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries? |
| title_short | Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries? |
| title_sort | is ajcc uicc staging still appropriate for head and neck cancers in developing countries |
| url | https://doi.org/10.1177/2473974X20938313 |
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