Cerebellum and Ocular Motor Control
An intact cerebellum is a prerequisite for optimal ocular motor performance. The cerebellum fine-tunes each of the subtypes of eye movements so they work together to bring and maintain images of objects of interest on the fovea. Here we review the major aspects of the contribution of the cerebellum...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2011-09-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fneur.2011.00053/full |
| _version_ | 1819056159358713856 |
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| author | Amir eKheradmand David S. Zee |
| author_facet | Amir eKheradmand David S. Zee |
| author_sort | Amir eKheradmand |
| collection | DOAJ |
| description | An intact cerebellum is a prerequisite for optimal ocular motor performance. The cerebellum fine-tunes each of the subtypes of eye movements so they work together to bring and maintain images of objects of interest on the fovea. Here we review the major aspects of the contribution of the cerebellum to ocular motor control. The approach will be based on structural-functional correlation, combining the effects of lesions and the results from physiologic studies, with the emphasis on the cerebellar regions known to be most closely related to ocular motor function: 1) the flocculus/paraflocculus for high-frequency (brief) vestibular responses, sustained pursuit eye movements and gaze-holding, 2) the nodulus/ventral uvula for low-frequency (sustained) vestibular responses, and 3) the dorsal oculomotor vermis and its target in the posterior portion of the fastigial nucleus (the fastigial oculomotor region) for saccades and pursuit initiation. |
| first_indexed | 2024-12-21T13:18:59Z |
| format | Article |
| id | doaj.art-2a9335e3b0284b6f874f1b0a4426d913 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-21T13:18:59Z |
| publishDate | 2011-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-2a9335e3b0284b6f874f1b0a4426d9132022-12-21T19:02:38ZengFrontiers Media S.A.Frontiers in Neurology1664-22952011-09-01210.3389/fneur.2011.0005311499Cerebellum and Ocular Motor ControlAmir eKheradmand0David S. Zee1Johns Hopkins University School of MedicineJohns Hopkins University School of MedicineAn intact cerebellum is a prerequisite for optimal ocular motor performance. The cerebellum fine-tunes each of the subtypes of eye movements so they work together to bring and maintain images of objects of interest on the fovea. Here we review the major aspects of the contribution of the cerebellum to ocular motor control. The approach will be based on structural-functional correlation, combining the effects of lesions and the results from physiologic studies, with the emphasis on the cerebellar regions known to be most closely related to ocular motor function: 1) the flocculus/paraflocculus for high-frequency (brief) vestibular responses, sustained pursuit eye movements and gaze-holding, 2) the nodulus/ventral uvula for low-frequency (sustained) vestibular responses, and 3) the dorsal oculomotor vermis and its target in the posterior portion of the fastigial nucleus (the fastigial oculomotor region) for saccades and pursuit initiation.http://journal.frontiersin.org/Journal/10.3389/fneur.2011.00053/fullsaccadevestibularpursuitFastigialFlocculusNodulus |
| spellingShingle | Amir eKheradmand David S. Zee Cerebellum and Ocular Motor Control Frontiers in Neurology saccade vestibular pursuit Fastigial Flocculus Nodulus |
| title | Cerebellum and Ocular Motor Control |
| title_full | Cerebellum and Ocular Motor Control |
| title_fullStr | Cerebellum and Ocular Motor Control |
| title_full_unstemmed | Cerebellum and Ocular Motor Control |
| title_short | Cerebellum and Ocular Motor Control |
| title_sort | cerebellum and ocular motor control |
| topic | saccade vestibular pursuit Fastigial Flocculus Nodulus |
| url | http://journal.frontiersin.org/Journal/10.3389/fneur.2011.00053/full |
| work_keys_str_mv | AT amirekheradmand cerebellumandocularmotorcontrol AT davidszee cerebellumandocularmotorcontrol |