Knockdown of the stem cell marker Musashi-1 inhibits endometrial cancer growth and sensitizes cells to radiation

Knockdown of the stem cell marker Musashi-1 inhibits endometrial cancer growth and sensitizes cells to radiation

Abstract Background Endometrial carcinoma is the most common gynecological cancer in Europe. Musashi-1 is known to be a key regulator of endometrial cancer stem cells and a negative prognostic marker. In the present study, we aimed to understand growth and gene expression patterns in endometrial car...

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Bibliographic Details
Main Authors: Isabel Falke, Fabian M. Troschel, Heike Palenta, Maria T. Löblein, Kathrin Brüggemann, Katrin Borrmann, Hans Theodor Eich, Martin Götte, Burkhard Greve
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Stem Cell Research & Therapy
Subjects:
Musashi-1
Cancer stem cell
Endometrial cancer
Proliferation
Radioresistance
Online Access:https://doi.org/10.1186/s13287-022-02891-3

Internet

https://doi.org/10.1186/s13287-022-02891-3

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