Knockdown of the stem cell marker Musashi-1 inhibits endometrial cancer growth and sensitizes cells to radiation
Abstract Background Endometrial carcinoma is the most common gynecological cancer in Europe. Musashi-1 is known to be a key regulator of endometrial cancer stem cells and a negative prognostic marker. In the present study, we aimed to understand growth and gene expression patterns in endometrial car...
Main Authors: | Isabel Falke, Fabian M. Troschel, Heike Palenta, Maria T. Löblein, Kathrin Brüggemann, Katrin Borrmann, Hans Theodor Eich, Martin Götte, Burkhard Greve |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-05-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-022-02891-3 |
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