Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response

Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response

Summary: Metabolic adaptations regulate the response of macrophages to infection. The contributions of metabolism to macrophage interactions with the emerging fungal pathogen Candida auris are poorly understood. Here, we show that C. auris-infected macrophages undergo immunometabolic reprogramming a...

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Bibliographic Details
Main Authors: Harshini Weerasinghe, Claudia Simm, Tirta Mario Djajawi, Irma Tedja, Tricia L. Lo, Daniel S. Simpson, David Shasha, Naama Mizrahi, Françios A.B. Olivier, Mary Speir, Kate E. Lawlor, Ronen Ben-Ami, Ana Traven
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005338

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