Developmental Abnormalities of Teeth in Children With Nephrotic Syndrome
Introduction: Treatment with glucocorticoids in children with nephrotic syndrome can be the cause of developmental disorders of the masticatory organ and bone or teeth abnormalities. The aim was to assess the frequency and type of dental abnormalities and the correlation of their occurrence with a d...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-08-01
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| Series: | International Dental Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0020653921002653 |
| _version_ | 1811297173283799040 |
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| author | Paula Piekoszewska-Ziętek Dorota Olczak-Kowalczyk Małgorzata Pańczyk-Tomaszewska Dariusz Gozdowski |
| author_facet | Paula Piekoszewska-Ziętek Dorota Olczak-Kowalczyk Małgorzata Pańczyk-Tomaszewska Dariusz Gozdowski |
| author_sort | Paula Piekoszewska-Ziętek |
| collection | DOAJ |
| description | Introduction: Treatment with glucocorticoids in children with nephrotic syndrome can be the cause of developmental disorders of the masticatory organ and bone or teeth abnormalities. The aim was to assess the frequency and type of dental abnormalities and the correlation of their occurrence with a dosage of glucocorticoids and treatment time in children with idiopathic nephrotic syndrome. Methods: The study group consisted of 31 patients aged 5 to 17 diagnosed with idiopathic steroid-sensitive nephrotic syndrome and 33 overall healthy children. The studies included clinical evaluation of dentition, radiologic diagnostics, and statistical analysis. Results: In the study group, 77.4% of patients were diagnosed with abnormalities in dental development. Tooth number disorders, presence of persistent deciduous teeth and impacted teeth, abnormal crown or root shape, developmental defects of enamel, pulp stones, and bone structure disorders were identified. Statistical analysis showed significant differences in the average treatment time of glucocorticoids in patients without and with tooth developmental abnormalities. Conclusions: Long-term use of glucocorticoids in children with nephrotic syndrome promotes the occurrence of developmental abnormalities of the teeth, calcification of the pulp, and disorders of bone tissue metabolism. For this reason, patients with steroid-sensitive nephrotic syndrome should be under the constant care of a dentist. |
| first_indexed | 2024-04-13T06:00:12Z |
| format | Article |
| id | doaj.art-2aa163681bed4e2eb98112e134ec0508 |
| institution | Directory Open Access Journal |
| issn | 0020-6539 |
| language | English |
| last_indexed | 2024-04-13T06:00:12Z |
| publishDate | 2022-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Dental Journal |
| spelling | doaj.art-2aa163681bed4e2eb98112e134ec05082022-12-22T02:59:28ZengElsevierInternational Dental Journal0020-65392022-08-01724572577Developmental Abnormalities of Teeth in Children With Nephrotic SyndromePaula Piekoszewska-Ziętek0Dorota Olczak-Kowalczyk1Małgorzata Pańczyk-Tomaszewska2Dariusz Gozdowski3Department of Paediatric Dentistry, Medical University of Warsaw, Warsaw, PolandDepartment of Paediatric Dentistry, Medical University of Warsaw, Warsaw, Poland; Corresponding author. Dorota Olczak-Kowalczyk, Binieckiego 6, 02-097 Warszawa, Poland.Paediatrics and Nephrology Cathedra and Clinic, Medical University of Warsaw, Warsaw, PolandDepartment of Experimental Statistics and Bioinformatics, Warsaw University of Life Science, Warsaw, PolandIntroduction: Treatment with glucocorticoids in children with nephrotic syndrome can be the cause of developmental disorders of the masticatory organ and bone or teeth abnormalities. The aim was to assess the frequency and type of dental abnormalities and the correlation of their occurrence with a dosage of glucocorticoids and treatment time in children with idiopathic nephrotic syndrome. Methods: The study group consisted of 31 patients aged 5 to 17 diagnosed with idiopathic steroid-sensitive nephrotic syndrome and 33 overall healthy children. The studies included clinical evaluation of dentition, radiologic diagnostics, and statistical analysis. Results: In the study group, 77.4% of patients were diagnosed with abnormalities in dental development. Tooth number disorders, presence of persistent deciduous teeth and impacted teeth, abnormal crown or root shape, developmental defects of enamel, pulp stones, and bone structure disorders were identified. Statistical analysis showed significant differences in the average treatment time of glucocorticoids in patients without and with tooth developmental abnormalities. Conclusions: Long-term use of glucocorticoids in children with nephrotic syndrome promotes the occurrence of developmental abnormalities of the teeth, calcification of the pulp, and disorders of bone tissue metabolism. For this reason, patients with steroid-sensitive nephrotic syndrome should be under the constant care of a dentist.http://www.sciencedirect.com/science/article/pii/S0020653921002653Nephrotic syndromeGlucocorticoidsDevelopmental defects of enamelOral cavity |
| spellingShingle | Paula Piekoszewska-Ziętek Dorota Olczak-Kowalczyk Małgorzata Pańczyk-Tomaszewska Dariusz Gozdowski Developmental Abnormalities of Teeth in Children With Nephrotic Syndrome International Dental Journal Nephrotic syndrome Glucocorticoids Developmental defects of enamel Oral cavity |
| title | Developmental Abnormalities of Teeth in Children With Nephrotic Syndrome |
| title_full | Developmental Abnormalities of Teeth in Children With Nephrotic Syndrome |
| title_fullStr | Developmental Abnormalities of Teeth in Children With Nephrotic Syndrome |
| title_full_unstemmed | Developmental Abnormalities of Teeth in Children With Nephrotic Syndrome |
| title_short | Developmental Abnormalities of Teeth in Children With Nephrotic Syndrome |
| title_sort | developmental abnormalities of teeth in children with nephrotic syndrome |
| topic | Nephrotic syndrome Glucocorticoids Developmental defects of enamel Oral cavity |
| url | http://www.sciencedirect.com/science/article/pii/S0020653921002653 |
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