An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion

Abstract The abscopal effect without concomitant immunotherapy is a rare event, including among cases of lung cancer. Furthermore, the occurrence of limited abscopal effect for only a single lesion in the metastatic organ consistent with the irradiated organ would be an even more rare event. A 94‐ye...

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Bibliographic Details
Main Authors: Tadashi Sakaguchi, Kentaro Ito, Kentaro Fujiwara, Yoichi Nishii, Satoru Ochiai, Yoshihito Nomoto, Osamu Hataji
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Thoracic Cancer
Subjects:
Online Access:https://doi.org/10.1111/1759-7714.14551
Description
Summary:Abstract The abscopal effect without concomitant immunotherapy is a rare event, including among cases of lung cancer. Furthermore, the occurrence of limited abscopal effect for only a single lesion in the metastatic organ consistent with the irradiated organ would be an even more rare event. A 94‐year‐old man was diagnosed with advanced lung cancer with osteolytic bone metastases in his right iliac bone, and the right side of his axial vertebrae. After palliative radiation therapy to the right iliac lesion for pain relief without other anticancer therapy, the axial vertebral osteolytic lesion disappeared despite no reduction in the other lesions. This case furthers our understanding of the pathogenesis of the abscopal effect.
ISSN:1759-7706
1759-7714