Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic Concept
Essential oils (EOs) have stability problems, including volatility, oxidation, photosensitivity, heat sensitivity, humidity sensitivity, pH sensitivity, and ion sensitivity. A drug delivery system is an effective way to stabilize EOs, especially due to the protective effect of polymeric drug carrier...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/15/16/3338 |
| _version_ | 1797583398628229120 |
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| author | Xue-Yee Lim Jing Li Hong-Mei Yin Mu He Ling Li Tong Zhang |
| author_facet | Xue-Yee Lim Jing Li Hong-Mei Yin Mu He Ling Li Tong Zhang |
| author_sort | Xue-Yee Lim |
| collection | DOAJ |
| description | Essential oils (EOs) have stability problems, including volatility, oxidation, photosensitivity, heat sensitivity, humidity sensitivity, pH sensitivity, and ion sensitivity. A drug delivery system is an effective way to stabilize EOs, especially due to the protective effect of polymeric drug carriers. Polysaccharides are frequently employed as drug carrier materials because they are highly safe, come in a variety of forms, and have plentiful sources. Interestingly, the EO drug delivery system is based on the biomimetic concept since it corresponds to the structure of plant tissue. In this paper, we associate the biomimetic plant-like structures of the EO drug delivery system with the natural forms of EO in plant tissues, and summarize the characteristics of polysaccharide-based drug carriers for EO protection. Thus, we highlight the research progress on polysaccharides and their modified materials, including gum arabic, starch, cellulose, chitosan, sodium alginate, pectin, and pullulan, and their use as biomimetic drug carriers for EO preparations due to their abilities and potential for EO protection. |
| first_indexed | 2024-03-10T23:38:21Z |
| format | Article |
| id | doaj.art-2aae7bf6a8be4ecf8adeb12e02d37978 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T23:38:21Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-2aae7bf6a8be4ecf8adeb12e02d379782023-11-19T02:42:39ZengMDPI AGPolymers2073-43602023-08-011516333810.3390/polym15163338Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic ConceptXue-Yee Lim0Jing Li1Hong-Mei Yin2Mu He3Ling Li4Tong Zhang5School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaJiangsu Kanion Pharmaceuticals Co., Ltd., Lianyungang 222001, ChinaSchool of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaEssential oils (EOs) have stability problems, including volatility, oxidation, photosensitivity, heat sensitivity, humidity sensitivity, pH sensitivity, and ion sensitivity. A drug delivery system is an effective way to stabilize EOs, especially due to the protective effect of polymeric drug carriers. Polysaccharides are frequently employed as drug carrier materials because they are highly safe, come in a variety of forms, and have plentiful sources. Interestingly, the EO drug delivery system is based on the biomimetic concept since it corresponds to the structure of plant tissue. In this paper, we associate the biomimetic plant-like structures of the EO drug delivery system with the natural forms of EO in plant tissues, and summarize the characteristics of polysaccharide-based drug carriers for EO protection. Thus, we highlight the research progress on polysaccharides and their modified materials, including gum arabic, starch, cellulose, chitosan, sodium alginate, pectin, and pullulan, and their use as biomimetic drug carriers for EO preparations due to their abilities and potential for EO protection.https://www.mdpi.com/2073-4360/15/16/3338polysaccharidesessential oilbiomimeticdrug delivery systemstabilityemulsion |
| spellingShingle | Xue-Yee Lim Jing Li Hong-Mei Yin Mu He Ling Li Tong Zhang Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic Concept Polymers polysaccharides essential oil biomimetic drug delivery system stability emulsion |
| title | Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic Concept |
| title_full | Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic Concept |
| title_fullStr | Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic Concept |
| title_full_unstemmed | Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic Concept |
| title_short | Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic Concept |
| title_sort | stabilization of essential oil polysaccharide based drug delivery system with plant like structure based on biomimetic concept |
| topic | polysaccharides essential oil biomimetic drug delivery system stability emulsion |
| url | https://www.mdpi.com/2073-4360/15/16/3338 |
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