Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes

Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes

Influenza continues to represent a major threat to public health, and the development of monoclonal antibodies (mAbs) that provide broad protection remains a key avenue for therapeutic development. Here, the authors demonstrate the molecular basis of neutralization for a human bnAb (PN-SIA28) agains...

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Bibliographic Details
Main Authors: Yulu Chen, Fei Wang, Liwei Yin, Haihai Jiang, Xishan Lu, Yuhai Bi, Wei Zhang, Yi Shi, Roberto Burioni, Zhou Tong, Hao Song, Jianxun Qi, George F. Gao
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35236-y

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