Pulmonary homograft dysfunction after Ross procedure in adults: a single center experience
The Ross procedure was first proposed by Donald Ross in 1967. Numerous studies show excellent long-term outcomes of the Ross operation. One of its disadvantages is the intervention on two valves due to pulmonary homograft dysfunction.Aim. To study long-term outcomes of pulmonary homograft use after...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2022-09-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/4804 |
| _version_ | 1826560977374543872 |
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| author | S. T. Enginoev D. А. Kondratiev A. A. Zenkov G. M. Magomedov T. K. Rashidova A. A. Abdurakhmanov I. I. Chernov D. G. Tarasov |
| author_facet | S. T. Enginoev D. А. Kondratiev A. A. Zenkov G. M. Magomedov T. K. Rashidova A. A. Abdurakhmanov I. I. Chernov D. G. Tarasov |
| author_sort | S. T. Enginoev |
| collection | DOAJ |
| description | The Ross procedure was first proposed by Donald Ross in 1967. Numerous studies show excellent long-term outcomes of the Ross operation. One of its disadvantages is the intervention on two valves due to pulmonary homograft dysfunction.Aim. To study long-term outcomes of pulmonary homograft use after Ross operation (cumulative incidence of pulmonary homograft dysfunction, freedom from reoperation on pulmonary homograft, long-term survival, predictors of pulmonary homograft dysfunction) using data from one Russian center.Material and methods. A retrospective study included patients aged 18 years and older with aortic valve disease who underwent Ross procedure from April 2009 to December 2020 by a single surgeon. The age of the patients was 35 (26-44) years (men, 159 (75%)). Infective endocarditis as a cause of aortic valve pathology was diagnosed in 55 (26%) patients. Bicuspid aortic valve was diagnosed in 131 (62%) patients. The median follow-up period was 79 (26,5102,7) months.Results. Combined interventions were performed in 40 cases (18,9%). The modified Ross procedure was used in 54 (25,5%) cases (intra-aortic — 29, using Dacron tube graft — 25). Inhospital mortality was 0,5%. The 5- and 10-year allcause survival rates were 98,5% and 95,4%, while the 10-year cumulative pulmonary valve reoperation rate and pulmonary homograft dysfunction was 4,6% and 35,2%, respectively. The only factor affecting pulmonary homograft dysfunction was patient age ≤30 years (odds ratio =0,2 with 95% confidence interval: 0,06-0,7; p=0,02).Conclusion. Fresh pulmonary homografts have a low incidence of dysfunction and reintervention after Ross procedure. Young age is the only independent risk factor for pulmonary homograft dysfunction. |
| first_indexed | 2024-04-09T20:43:06Z |
| format | Article |
| id | doaj.art-2ab305e95e26430d81f4837851840637 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:24:51Z |
| publishDate | 2022-09-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-2ab305e95e26430d81f48378518406372025-03-02T11:42:59Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202022-09-0127810.15829/1560-4071-2022-48043452Pulmonary homograft dysfunction after Ross procedure in adults: a single center experienceS. T. Enginoev0D. А. Kondratiev1A. A. Zenkov2G. M. Magomedov3T. K. Rashidova4A. A. Abdurakhmanov5I. I. Chernov6D. G. Tarasov7Federal Center for Cardiovascular Surgery; Astrakhan State Medical UniversityFederal Center for Cardiovascular SurgeryFederal Center for Cardiovascular SurgeryFederal Center for Cardiovascular SurgeryFederal Center for Cardiovascular SurgeryAstrakhan State Medical UniversityFederal Center for Cardiovascular SurgeryFederal Center for Cardiovascular SurgeryThe Ross procedure was first proposed by Donald Ross in 1967. Numerous studies show excellent long-term outcomes of the Ross operation. One of its disadvantages is the intervention on two valves due to pulmonary homograft dysfunction.Aim. To study long-term outcomes of pulmonary homograft use after Ross operation (cumulative incidence of pulmonary homograft dysfunction, freedom from reoperation on pulmonary homograft, long-term survival, predictors of pulmonary homograft dysfunction) using data from one Russian center.Material and methods. A retrospective study included patients aged 18 years and older with aortic valve disease who underwent Ross procedure from April 2009 to December 2020 by a single surgeon. The age of the patients was 35 (26-44) years (men, 159 (75%)). Infective endocarditis as a cause of aortic valve pathology was diagnosed in 55 (26%) patients. Bicuspid aortic valve was diagnosed in 131 (62%) patients. The median follow-up period was 79 (26,5102,7) months.Results. Combined interventions were performed in 40 cases (18,9%). The modified Ross procedure was used in 54 (25,5%) cases (intra-aortic — 29, using Dacron tube graft — 25). Inhospital mortality was 0,5%. The 5- and 10-year allcause survival rates were 98,5% and 95,4%, while the 10-year cumulative pulmonary valve reoperation rate and pulmonary homograft dysfunction was 4,6% and 35,2%, respectively. The only factor affecting pulmonary homograft dysfunction was patient age ≤30 years (odds ratio =0,2 with 95% confidence interval: 0,06-0,7; p=0,02).Conclusion. Fresh pulmonary homografts have a low incidence of dysfunction and reintervention after Ross procedure. Young age is the only independent risk factor for pulmonary homograft dysfunction.https://russjcardiol.elpub.ru/jour/article/view/4804acquired heart diseaseaortic stenosisaortic regurgitationross procedurehomograftpulmonary valve dysfunction |
| spellingShingle | S. T. Enginoev D. А. Kondratiev A. A. Zenkov G. M. Magomedov T. K. Rashidova A. A. Abdurakhmanov I. I. Chernov D. G. Tarasov Pulmonary homograft dysfunction after Ross procedure in adults: a single center experience Российский кардиологический журнал acquired heart disease aortic stenosis aortic regurgitation ross procedure homograft pulmonary valve dysfunction |
| title | Pulmonary homograft dysfunction after Ross procedure in adults: a single center experience |
| title_full | Pulmonary homograft dysfunction after Ross procedure in adults: a single center experience |
| title_fullStr | Pulmonary homograft dysfunction after Ross procedure in adults: a single center experience |
| title_full_unstemmed | Pulmonary homograft dysfunction after Ross procedure in adults: a single center experience |
| title_short | Pulmonary homograft dysfunction after Ross procedure in adults: a single center experience |
| title_sort | pulmonary homograft dysfunction after ross procedure in adults a single center experience |
| topic | acquired heart disease aortic stenosis aortic regurgitation ross procedure homograft pulmonary valve dysfunction |
| url | https://russjcardiol.elpub.ru/jour/article/view/4804 |
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