Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells

Understanding epigenetic mechanisms regulating embryonic stem cell (ESC) differentiation to endothelial cells may lead to increased efficiency of generation of vessel wall endothelial cells needed for vascular engineering. Here we demonstrated that the histone demethylases KDM4A and KDM4C played an...

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Bibliographic Details
Main Authors: Liangtang Wu, Kishore K. Wary, Sergei Revskoy, Xiaopei Gao, Kitman Tsang, Yulia A. Komarova, Jalees Rehman, Asrar B. Malik
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115001599

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