Study the adverse role of histological and oxidative effects of ginger (Zingiberaceae) and cadmium chloride in liver tissue of rabbits
In this study, was investigate the ability of Ginger to adversely histological and physiology effect of cadmium in the liver tissue of rabbit, Ginger is source of antioxidants was administered orally to prevent the adverse effects of cadmium (cd). Twenty four male rabbits were randomized into 3...
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| Format: | Article |
| Language: | English |
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Faculty of Veterinary Medicine, University of Kufa
2012-06-01
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| Series: | Kufa Journal for Veterinary Medical Sciences |
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| Online Access: | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4067 |
| _version_ | 1797363997485301760 |
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| author | H. A. Al-Ameer |
| author_facet | H. A. Al-Ameer |
| author_sort | H. A. Al-Ameer |
| collection | DOAJ |
| description |
In this study, was investigate the ability of Ginger to adversely histological and physiology effect of cadmium in the liver tissue of rabbit, Ginger is source of antioxidants was administered orally to prevent the adverse effects of cadmium (cd). Twenty four male rabbits were randomized into 3 groups (n = 8), were used for this study. Animals in group (1) served as the control and were drinking distilled water. Animals in groups (2) were drinking2% cadmium chloride. Group (3) animals were, in addition to drinking cadmium, treated with 250 mg/kg of ginger. All treatments were for 12 weeks.
The results showed that cadmium caused a significant (p<0.05) reduction in plasma superoxide dismutase and catalase activity, but a significant increase (p<0.05) in plasma malondialdehyde concentration with histological changes in liver cell such as necrosis, hemorrhage with aggregation of some toxic spot as (black spot),protein cast with epithelial cell in group 3 comparison with control and other group , using ginger cause to modified these harmful effects. These findings lead to the conclusion that ginger significantly decreased (p<0.05) the adverse toxic harmful effects of cadmium exposure on the liver as oxidative stress.
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| first_indexed | 2024-03-08T16:29:02Z |
| format | Article |
| id | doaj.art-2ab5efed15684edf9ded598f9f438a95 |
| institution | Directory Open Access Journal |
| issn | 2077-9798 2959-8478 |
| language | English |
| last_indexed | 2024-03-08T16:29:02Z |
| publishDate | 2012-06-01 |
| publisher | Faculty of Veterinary Medicine, University of Kufa |
| record_format | Article |
| series | Kufa Journal for Veterinary Medical Sciences |
| spelling | doaj.art-2ab5efed15684edf9ded598f9f438a952024-01-06T10:25:04ZengFaculty of Veterinary Medicine, University of KufaKufa Journal for Veterinary Medical Sciences2077-97982959-84782012-06-013110.36326/kjvs/2012/v3i14067Study the adverse role of histological and oxidative effects of ginger (Zingiberaceae) and cadmium chloride in liver tissue of rabbitsH. A. Al-Ameer In this study, was investigate the ability of Ginger to adversely histological and physiology effect of cadmium in the liver tissue of rabbit, Ginger is source of antioxidants was administered orally to prevent the adverse effects of cadmium (cd). Twenty four male rabbits were randomized into 3 groups (n = 8), were used for this study. Animals in group (1) served as the control and were drinking distilled water. Animals in groups (2) were drinking2% cadmium chloride. Group (3) animals were, in addition to drinking cadmium, treated with 250 mg/kg of ginger. All treatments were for 12 weeks. The results showed that cadmium caused a significant (p<0.05) reduction in plasma superoxide dismutase and catalase activity, but a significant increase (p<0.05) in plasma malondialdehyde concentration with histological changes in liver cell such as necrosis, hemorrhage with aggregation of some toxic spot as (black spot),protein cast with epithelial cell in group 3 comparison with control and other group , using ginger cause to modified these harmful effects. These findings lead to the conclusion that ginger significantly decreased (p<0.05) the adverse toxic harmful effects of cadmium exposure on the liver as oxidative stress. https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4067Animalscadmium chloridemale rabbitsnecrosis |
| spellingShingle | H. A. Al-Ameer Study the adverse role of histological and oxidative effects of ginger (Zingiberaceae) and cadmium chloride in liver tissue of rabbits Kufa Journal for Veterinary Medical Sciences Animals cadmium chloride male rabbits necrosis |
| title | Study the adverse role of histological and oxidative effects of ginger (Zingiberaceae) and cadmium chloride in liver tissue of rabbits |
| title_full | Study the adverse role of histological and oxidative effects of ginger (Zingiberaceae) and cadmium chloride in liver tissue of rabbits |
| title_fullStr | Study the adverse role of histological and oxidative effects of ginger (Zingiberaceae) and cadmium chloride in liver tissue of rabbits |
| title_full_unstemmed | Study the adverse role of histological and oxidative effects of ginger (Zingiberaceae) and cadmium chloride in liver tissue of rabbits |
| title_short | Study the adverse role of histological and oxidative effects of ginger (Zingiberaceae) and cadmium chloride in liver tissue of rabbits |
| title_sort | study the adverse role of histological and oxidative effects of ginger zingiberaceae and cadmium chloride in liver tissue of rabbits |
| topic | Animals cadmium chloride male rabbits necrosis |
| url | https://journal.uokufa.edu.iq/index.php/kjvs/article/view/4067 |
| work_keys_str_mv | AT haalameer studytheadverseroleofhistologicalandoxidativeeffectsofgingerzingiberaceaeandcadmiumchlorideinlivertissueofrabbits |