Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction

Dimeric Thymosin β4 Loaded Nanofibrous Interface Enhanced Regeneration of Muscular Artery in Aging Body through Modulating Perivascular Adipose Stem Cell–Macrophage Interaction

Abstract Regenerating nonthrombotic and compliant artery, especially in the aging body, remains a major surgical challenge, mainly owing to the inadequate knowledge of the major cell sources contributing to arterial regeneration and insufficient bioactivity of delivered peptides in grafts. Ultrathin...

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Bibliographic Details
Main Authors: Wanli Chen, Sansan Jia, Xinchi Zhang, Siqian Zhang, Huan Liu, Xin Yang, Cun Zhang, Wei Wu
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Advanced Science
Subjects:
aging
arterial regeneration
biodegradable grafts
dimeric thymosin‐β4
M2 macrophages
Online Access:https://doi.org/10.1002/advs.201903307

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