Activation of the RMTg Nucleus by Chemogenetic Techniques Alleviates the Learning and Memory Impairment in APP/PS1 Mice

Activation of the RMTg Nucleus by Chemogenetic Techniques Alleviates the Learning and Memory Impairment in APP/PS1 Mice

Ling Zheng,1– 3 Zhenjie Wang,2 Yujia Liu,4 Jiapei Zhao,5 Saie Huang1,3 1Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, People’s Republic of China; 2College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medic...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Zheng L, Wang Z, Liu Y, Zhao J, Huang S
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	Dove Medical Press 2022-12-01
Σειρά:	Neuropsychiatric Disease and Treatment
Θέματα:	alzheimer’s disease chemical genetics rostromedial tegmental nucleus rmtg learning and memory amyloid-β aβ.
Διαθέσιμο Online:	https://www.dovepress.com/activation-of-the-rmtg-nucleus-by-chemogenetic-techniques-alleviates-t-peer-reviewed-fulltext-article-NDT

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ανά: Masuo Ohno, κ.ά.
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ανά: Qiong Wu, κ.ά.
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ανά: Christa Dang, κ.ά.
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ανά: Yongjia Zhao, κ.ά.
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ανά: Yunjie Yang, κ.ά.
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ανά: Di Xue, κ.ά.
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ανά: M. Paul Murphy, κ.ά.
Έκδοση: (2007-09-01)

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ανά: Mehdi Mehdizadeh, κ.ά.
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