A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management
The implications of endoscopic ultrasound (EUS) have expanded considerably in recent years to cover more fields in invasive gastroenterology practice, as both an investigative and therapeutic modality. The utility of EUS in the diagnosis and management of focal liver lesions has gained a special att...
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| Format: | Article |
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MDPI AG
2020-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/10/9/688 |
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| author | Wisam Sbeit Anas Kadah Amir Mari Mahmud Mahamid Tawfik Khoury |
| author_facet | Wisam Sbeit Anas Kadah Amir Mari Mahmud Mahamid Tawfik Khoury |
| author_sort | Wisam Sbeit |
| collection | DOAJ |
| description | The implications of endoscopic ultrasound (EUS) have expanded considerably in recent years to cover more fields in invasive gastroenterology practice, as both an investigative and therapeutic modality. The utility of EUS in the diagnosis and management of focal liver lesions has gained a special attractiveness recently. The EUS probe proximity to the liver and its excellent spatial resolution enables real-time images coupled with several enhancement techniques, such as contrast-enhanced (CE) EUS. Aside from its notable capability to execute targeted biopsies and therapeutic interventions, EUS has developed into a hopeful therapeutic tool for the management of solid liver lesions. Herein, we provide a comprehensive state-of-the-art review on the efficacy and safety of EUS in the diagnosis and management of focal solid liver lesions. Medline/PubMed and Embase database searches were conducted by two separate authors (T.K. and W.S.), all relevant studies were assessed, and relevant data was extracted and fully reported. EUS-guided diagnosis of focal liver lesions by sonographic morphologic appearance and cytological and histopathological finding of biopsies obtained via fine needle aspiration/biopsy have been shown to significantly improve the diagnosis of solid liver lesions compared with traditional imaging tools. Similarly, EUS-guided treatment has been shown to consistently have excellent technical success, high efficacy, and minor adverse events. The evolving valuable evidences of EUS utility might satisfy the unmet need of optimizing management of focal solid liver lesions. |
| first_indexed | 2024-03-10T16:23:17Z |
| format | Article |
| id | doaj.art-2ab94ea0aae542e4ae3bdfa3467d5b9b |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T16:23:17Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-2ab94ea0aae542e4ae3bdfa3467d5b9b2023-11-20T13:25:14ZengMDPI AGDiagnostics2075-44182020-09-0110968810.3390/diagnostics10090688A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and ManagementWisam Sbeit0Anas Kadah1Amir Mari2Mahmud Mahamid3Tawfik Khoury4Department of Gastroenterology, Galilee Medical Center, Nahariya 22100, IsraelDepartment of Gastroenterology, Galilee Medical Center, Nahariya 22100, IsraelFaculty of Medicine in the Galilee, Bar-Ilan University, Safed 1311502, IsraelDepartment of Gastroenterology and Liver Diseases, Shaare Zedek Medical Center, Jerusalem 9103102, IsraelDepartment of Gastroenterology, Galilee Medical Center, Nahariya 22100, IsraelThe implications of endoscopic ultrasound (EUS) have expanded considerably in recent years to cover more fields in invasive gastroenterology practice, as both an investigative and therapeutic modality. The utility of EUS in the diagnosis and management of focal liver lesions has gained a special attractiveness recently. The EUS probe proximity to the liver and its excellent spatial resolution enables real-time images coupled with several enhancement techniques, such as contrast-enhanced (CE) EUS. Aside from its notable capability to execute targeted biopsies and therapeutic interventions, EUS has developed into a hopeful therapeutic tool for the management of solid liver lesions. Herein, we provide a comprehensive state-of-the-art review on the efficacy and safety of EUS in the diagnosis and management of focal solid liver lesions. Medline/PubMed and Embase database searches were conducted by two separate authors (T.K. and W.S.), all relevant studies were assessed, and relevant data was extracted and fully reported. EUS-guided diagnosis of focal liver lesions by sonographic morphologic appearance and cytological and histopathological finding of biopsies obtained via fine needle aspiration/biopsy have been shown to significantly improve the diagnosis of solid liver lesions compared with traditional imaging tools. Similarly, EUS-guided treatment has been shown to consistently have excellent technical success, high efficacy, and minor adverse events. The evolving valuable evidences of EUS utility might satisfy the unmet need of optimizing management of focal solid liver lesions.https://www.mdpi.com/2075-4418/10/9/688endoscopic ultrasound (EUS)liver diseasesdiagnosismanagement |
| spellingShingle | Wisam Sbeit Anas Kadah Amir Mari Mahmud Mahamid Tawfik Khoury A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management Diagnostics endoscopic ultrasound (EUS) liver diseases diagnosis management |
| title | A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management |
| title_full | A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management |
| title_fullStr | A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management |
| title_full_unstemmed | A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management |
| title_short | A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management |
| title_sort | comprehensive narrative review on the evolving role of endoscopic ultrasound in focal solid liver lesions diagnosis and management |
| topic | endoscopic ultrasound (EUS) liver diseases diagnosis management |
| url | https://www.mdpi.com/2075-4418/10/9/688 |
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