Anti-Tumor Efficacy of In Situ Vaccination Using Bacterial Outer Membrane Vesicles

Anti-Tumor Efficacy of In Situ Vaccination Using Bacterial Outer Membrane Vesicles

In situ vaccination (ISV) is a promising cancer immunotherapy strategy that consists of the intratumoral administration of immunostimulatory molecules (adjuvants). The rationale is that tumor antigens are abundant at the tumor site, and therefore, to elicit an effective anti-tumor immune response, a...

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Bibliographic Details
Main Authors: Elena Caproni, Riccardo Corbellari, Michele Tomasi, Samine J. Isaac, Silvia Tamburini, Ilaria Zanella, Martina Grigolato, Assunta Gagliardi, Mattia Benedet, Chiara Baraldi, Lorenzo Croia, Gabriele Di Lascio, Alvise Berti, Silvia Valensin, Erika Bellini, Matteo Parri, Alberto Grandi, Guido Grandi
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
cancer vaccines
neo-epitopes
personalized medicine
outer membrane vesicles (OMVs)
adjuvants
Online Access:https://www.mdpi.com/2072-6694/15/13/3328

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