3′ RNA-seq is superior to standard RNA-seq in cases of sparse data but inferior at identifying toxicity pathways in a model organism

3′ RNA-seq is superior to standard RNA-seq in cases of sparse data but inferior at identifying toxicity pathways in a model organism

Introduction: The application of RNA-sequencing has led to numerous breakthroughs related to investigating gene expression levels in complex biological systems. Among these are knowledge of how organisms, such as the vertebrate model organism zebrafish (Danio rerio), respond to toxicant exposure. Re...

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Bibliographic Details
Main Authors: Ryan S. McClure, Yvonne Rericha, Katrina M. Waters, Robyn L. Tanguay
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Bioinformatics
Subjects:
3′ RNA-seq
transcriptomics
toxicity pathways
zebrafish
functional enrichment
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2023.1234218/full

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