Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em>
Seven new sesquiterpenoids, lochmolins A–G (<strong>1</strong>–<strong>7</strong>), were isolated from a Taiwanese soft coral <em>Sinularia lochmodes</em>. The structures of these metabolites were elucidated by exten...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-07-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/10/7/1572 |
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| author | Jyh-Horng Sheu Chiung-Yao Huang Hui-Li Lin Kuo-Ping Shen Yen-Ju Tseng Chang-Feng Dai |
| author_facet | Jyh-Horng Sheu Chiung-Yao Huang Hui-Li Lin Kuo-Ping Shen Yen-Ju Tseng Chang-Feng Dai |
| author_sort | Jyh-Horng Sheu |
| collection | DOAJ |
| description | Seven new sesquiterpenoids, lochmolins A–G (<strong>1</strong>–<strong>7</strong>), were isolated from a Taiwanese soft coral <em>Sinularia lochmodes</em>. The structures of these metabolites were elucidated by extensive spectroscopic study. Compounds <strong>1</strong>–<strong>4</strong> were found to inhibit the accumulation of the LPS-induced pro-inflammatory COX-2 protein in RAW264.7 macrophage cells. |
| first_indexed | 2024-04-14T05:21:17Z |
| format | Article |
| id | doaj.art-2ad047b0d11e4f6da7ec5bd41976af62 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-14T05:21:17Z |
| publishDate | 2012-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-2ad047b0d11e4f6da7ec5bd41976af622022-12-22T02:10:11ZengMDPI AGMarine Drugs1660-33972012-07-011071572158110.3390/md10071572Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em>Jyh-Horng SheuChiung-Yao HuangHui-Li LinKuo-Ping ShenYen-Ju TsengChang-Feng DaiSeven new sesquiterpenoids, lochmolins A–G (<strong>1</strong>–<strong>7</strong>), were isolated from a Taiwanese soft coral <em>Sinularia lochmodes</em>. The structures of these metabolites were elucidated by extensive spectroscopic study. Compounds <strong>1</strong>–<strong>4</strong> were found to inhibit the accumulation of the LPS-induced pro-inflammatory COX-2 protein in RAW264.7 macrophage cells.http://www.mdpi.com/1660-3397/10/7/1572soft coral<em>Sinularia</em><em> </em><em>lochmodes</em>sesquiterpenesaromadendranegermacrane |
| spellingShingle | Jyh-Horng Sheu Chiung-Yao Huang Hui-Li Lin Kuo-Ping Shen Yen-Ju Tseng Chang-Feng Dai Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em> Marine Drugs soft coral <em>Sinularia</em><em> </em><em>lochmodes</em> sesquiterpenes aromadendrane germacrane |
| title | Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em> |
| title_full | Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em> |
| title_fullStr | Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em> |
| title_full_unstemmed | Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em> |
| title_short | Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em> |
| title_sort | lochmolins a g new sesquiterpenoids from the soft coral lt em gt sinularia lt em gt lt em gt lochmodes lt em gt |
| topic | soft coral <em>Sinularia</em><em> </em><em>lochmodes</em> sesquiterpenes aromadendrane germacrane |
| url | http://www.mdpi.com/1660-3397/10/7/1572 |
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