Aerobic exercise and metformin on intermuscular adipose tissue (IMAT): insights from multimodal MRI and histological changes in prediabetic rats

Aerobic exercise and metformin on intermuscular adipose tissue (IMAT): insights from multimodal MRI and histological changes in prediabetic rats

Abstract Background Physical exercise is the first-line intervention for prediabetes, and metformin is the most widely used oral insulin-sensitizing agent. Moreover, intermuscular adipose tissue (IMAT) directly affects insulin resistance by helping maintain glucose homeostasis. Here, we evaluated th...

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Bibliographic Details
Main Authors: Fuyao Yu, Chuan Xing, Yiping Fan, Yanping Liu, Peng Su, Qiuhua Yang, Yanbin Dong, Yang Hou, Shinong Pan
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Adipose tissue
Metformin
Aerobic exercise
Prediabetes
Multimodal imaging
Magnetic-resonance imaging
Online Access:https://doi.org/10.1186/s13098-023-01183-x

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