Mechanisms for Bile Acids CDCA- and DCA-Stimulated Hepatic Spexin Expression

Mechanisms for Bile Acids CDCA- and DCA-Stimulated Hepatic Spexin Expression

Spexin (SPX) is a novel peptide involved in glucose and lipid metabolism and suppresses hepatic total bile acid levels by inhibiting hepatic cholesterol 7α-hydroxylase 1 expression. As important mediators for glycolysis/gluconeogenesis and lipid metabolism, the effects of bile acids on SPX expressio...

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Bibliographic Details
Main Authors: Qi Lai, Yanhua Ma, Jin Bai, Min Zhuang, Shaofei Pei, Ni He, Junlin Yin, Baomin Fan, Zhaoxiang Bian, Guangzhi Zeng, Chengyuan Lin
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
spexin
bile acid
liver cells
gene transcription
Online Access:https://www.mdpi.com/2073-4409/11/14/2159

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