Successful Pulmonary Endarterectomy after Acute Pulmonary Embolism and Reversal of Acute Cor Pulmonale in an 11-Year-Old Boy with Nephrotic Syndrome
Patients with nephrotic syndrome (NS) are at an increased risk for thromboembolic events, such as deep venous and arterial thrombosis and pulmonary embolism (PE). In general, PE in children differs from adults in incidence, predisposition, pathophysiology, presenting symptoms, and management strateg...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/10/1444 |
| _version_ | 1797474217168470016 |
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| author | Onyekachukwue Osakwe Bibhuti B. Das |
| author_facet | Onyekachukwue Osakwe Bibhuti B. Das |
| author_sort | Onyekachukwue Osakwe |
| collection | DOAJ |
| description | Patients with nephrotic syndrome (NS) are at an increased risk for thromboembolic events, such as deep venous and arterial thrombosis and pulmonary embolism (PE). In general, PE in children differs from adults in incidence, predisposition, pathophysiology, presenting symptoms, and management strategies. There is a lack of treatment guidelines for PE in children, and the management strategies are mostly extrapolated from adult data. This case report highlights the presentation of acute cor pulmonale due to massive PE associated with NS and a successful pulmonary endarterectomy that reversed the child’s pulmonary hypertension and normalized right ventricular function. |
| first_indexed | 2024-03-09T20:27:57Z |
| format | Article |
| id | doaj.art-2ad83b9a5b264d60a54cbf7cea564a75 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T20:27:57Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-2ad83b9a5b264d60a54cbf7cea564a752023-11-23T23:31:03ZengMDPI AGChildren2227-90672022-09-01910144410.3390/children9101444Successful Pulmonary Endarterectomy after Acute Pulmonary Embolism and Reversal of Acute Cor Pulmonale in an 11-Year-Old Boy with Nephrotic SyndromeOnyekachukwue Osakwe0Bibhuti B. Das1Department of Pediatrics, Division of Cardiology, University of Mississippi Medical Center, Jackson, MS 39216, USADepartment of Pediatrics, Division of Cardiology, University of Mississippi Medical Center, Jackson, MS 39216, USAPatients with nephrotic syndrome (NS) are at an increased risk for thromboembolic events, such as deep venous and arterial thrombosis and pulmonary embolism (PE). In general, PE in children differs from adults in incidence, predisposition, pathophysiology, presenting symptoms, and management strategies. There is a lack of treatment guidelines for PE in children, and the management strategies are mostly extrapolated from adult data. This case report highlights the presentation of acute cor pulmonale due to massive PE associated with NS and a successful pulmonary endarterectomy that reversed the child’s pulmonary hypertension and normalized right ventricular function.https://www.mdpi.com/2227-9067/9/10/1444acute pulmonary embolismchildnephrotic syndromepulmonary endarterectomy |
| spellingShingle | Onyekachukwue Osakwe Bibhuti B. Das Successful Pulmonary Endarterectomy after Acute Pulmonary Embolism and Reversal of Acute Cor Pulmonale in an 11-Year-Old Boy with Nephrotic Syndrome Children acute pulmonary embolism child nephrotic syndrome pulmonary endarterectomy |
| title | Successful Pulmonary Endarterectomy after Acute Pulmonary Embolism and Reversal of Acute Cor Pulmonale in an 11-Year-Old Boy with Nephrotic Syndrome |
| title_full | Successful Pulmonary Endarterectomy after Acute Pulmonary Embolism and Reversal of Acute Cor Pulmonale in an 11-Year-Old Boy with Nephrotic Syndrome |
| title_fullStr | Successful Pulmonary Endarterectomy after Acute Pulmonary Embolism and Reversal of Acute Cor Pulmonale in an 11-Year-Old Boy with Nephrotic Syndrome |
| title_full_unstemmed | Successful Pulmonary Endarterectomy after Acute Pulmonary Embolism and Reversal of Acute Cor Pulmonale in an 11-Year-Old Boy with Nephrotic Syndrome |
| title_short | Successful Pulmonary Endarterectomy after Acute Pulmonary Embolism and Reversal of Acute Cor Pulmonale in an 11-Year-Old Boy with Nephrotic Syndrome |
| title_sort | successful pulmonary endarterectomy after acute pulmonary embolism and reversal of acute cor pulmonale in an 11 year old boy with nephrotic syndrome |
| topic | acute pulmonary embolism child nephrotic syndrome pulmonary endarterectomy |
| url | https://www.mdpi.com/2227-9067/9/10/1444 |
| work_keys_str_mv | AT onyekachukwueosakwe successfulpulmonaryendarterectomyafteracutepulmonaryembolismandreversalofacutecorpulmonaleinan11yearoldboywithnephroticsyndrome AT bibhutibdas successfulpulmonaryendarterectomyafteracutepulmonaryembolismandreversalofacutecorpulmonaleinan11yearoldboywithnephroticsyndrome |