Promoter decoding of transcription factor dynamics involves a trade‐off between noise and control of gene expression

Abstract Numerous transcription factors (TFs) encode information about upstream signals in the dynamics of their activation, but how downstream genes decode these dynamics remains poorly understood. Using microfluidics to control the nucleocytoplasmic translocation dynamics of the budding yeast TF M...

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Bibliographic Details
Main Authors: Anders S Hansen, Erin K O'Shea
Format: Article
Language:English
Published: Springer Nature 2013-11-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2013.56