Endothelial Protein C Receptor (EPCR), Protease Activated Receptor-1 (PAR-1) and Their Interplay in Cancer Growth and Metastatic Dissemination

Endothelial protein C receptor (EPCR) and protease activated receptor 1 (PAR-1) by themselves play important role in cancer growth and dissemination. Moreover, interactions between the two receptors are essential for tumor progression. EPCR is a cell surface transmembrane glycoprotein localized pred...

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Bibliographic Details
Main Authors: Marek Z. Wojtukiewicz, Dominika Hempel, Ewa Sierko, Stephanie C. Tucker, Kenneth V. Honn
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/11/1/51