Severe Osteomalacia Related to Long-Term Intravenous Drug Abuse
Objective . We present the clinical, biochemical, and imaging findings of a woman with vitamin D deficiency and severe osteomalacia related to intravenous heroin addiction. Results . A 54-year-old woman with a medical history significant for long-standing heroin abuse presented with complaints of bo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-09-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/2324709614548797 |
| _version_ | 1818958260558888960 |
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| author | Leslie Gamache MD Mark R. Burge MD |
| author_facet | Leslie Gamache MD Mark R. Burge MD |
| author_sort | Leslie Gamache MD |
| collection | DOAJ |
| description | Objective . We present the clinical, biochemical, and imaging findings of a woman with vitamin D deficiency and severe osteomalacia related to intravenous heroin addiction. Results . A 54-year-old woman with a medical history significant for long-standing heroin abuse presented with complaints of bone pain, muscle cramping, and a left hip ulcer. She had been bed bound for approximately 1 year secondary to pain of uncertain etiology, and her husband was bringing her both food and drugs. She was admitted to the hospital for debridement of a right ischial ulcer. Further workup revealed osteomyelitis of the left hip and severe vitamin D deficiency. Radiologic evaluation demonstrated diffuse osteopenia with pseudofractures, as well as true fractures. Conclusion . This is the first case reported in the English literature of advanced osteomalacia resulting from a debilitating narcotic dependency. Vitamin D deficiency should be considered in patients with poor nutrition and prolonged sunlight deprivation from any cause. |
| first_indexed | 2024-12-20T11:22:55Z |
| format | Article |
| id | doaj.art-2adefb6652cc4e8b98b9964e724924b6 |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-12-20T11:22:55Z |
| publishDate | 2014-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-2adefb6652cc4e8b98b9964e724924b62022-12-21T19:42:27ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962014-09-01210.1177/232470961454879710.1177_2324709614548797Severe Osteomalacia Related to Long-Term Intravenous Drug AbuseLeslie Gamache MD0Mark R. Burge MD1Health One, Denver Endocrinology, Denver, CO, USAUniversity of New Mexico Health Sciences Center, Albuquerque, NM, USAObjective . We present the clinical, biochemical, and imaging findings of a woman with vitamin D deficiency and severe osteomalacia related to intravenous heroin addiction. Results . A 54-year-old woman with a medical history significant for long-standing heroin abuse presented with complaints of bone pain, muscle cramping, and a left hip ulcer. She had been bed bound for approximately 1 year secondary to pain of uncertain etiology, and her husband was bringing her both food and drugs. She was admitted to the hospital for debridement of a right ischial ulcer. Further workup revealed osteomyelitis of the left hip and severe vitamin D deficiency. Radiologic evaluation demonstrated diffuse osteopenia with pseudofractures, as well as true fractures. Conclusion . This is the first case reported in the English literature of advanced osteomalacia resulting from a debilitating narcotic dependency. Vitamin D deficiency should be considered in patients with poor nutrition and prolonged sunlight deprivation from any cause.https://doi.org/10.1177/2324709614548797 |
| spellingShingle | Leslie Gamache MD Mark R. Burge MD Severe Osteomalacia Related to Long-Term Intravenous Drug Abuse Journal of Investigative Medicine High Impact Case Reports |
| title | Severe Osteomalacia Related to Long-Term Intravenous Drug Abuse |
| title_full | Severe Osteomalacia Related to Long-Term Intravenous Drug Abuse |
| title_fullStr | Severe Osteomalacia Related to Long-Term Intravenous Drug Abuse |
| title_full_unstemmed | Severe Osteomalacia Related to Long-Term Intravenous Drug Abuse |
| title_short | Severe Osteomalacia Related to Long-Term Intravenous Drug Abuse |
| title_sort | severe osteomalacia related to long term intravenous drug abuse |
| url | https://doi.org/10.1177/2324709614548797 |
| work_keys_str_mv | AT lesliegamachemd severeosteomalaciarelatedtolongtermintravenousdrugabuse AT markrburgemd severeosteomalaciarelatedtolongtermintravenousdrugabuse |