Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH): study protocol for a randomized controlled trial
<p>Abstract</p> <p>Background</p> <p>Spontaneous intracerebral hemorrhage is a disease with high morbidity, high disability rate, high mortality, and high economic burden. Whether patients can benefit from surgical evacuation of hematomas is still controversial, especia...
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| Format: | Article |
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BMC
2012-06-01
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| Series: | BMC Neurology |
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| Online Access: | http://www.biomedcentral.com/1471-2377/12/34 |
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| author | Zan Xin Li Hao Liu Wenke Fang Yuan Ma Junpeng Lan Zhigang Li Xi Liu Xin You Chao |
| author_facet | Zan Xin Li Hao Liu Wenke Fang Yuan Ma Junpeng Lan Zhigang Li Xi Liu Xin You Chao |
| author_sort | Zan Xin |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Spontaneous intracerebral hemorrhage is a disease with high morbidity, high disability rate, high mortality, and high economic burden. Whether patients can benefit from surgical evacuation of hematomas is still controversial, especially for those with moderate-volume hematomas in the basal ganglia. This study is designed to compare the efficacy of endoscopic surgery and conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage.</p> <p>Methods</p> <p>Patients meet the criteria will be randomized into the endoscopic surgery group (endoscopic surgery for hematoma evacuation and the best medical treatment) or the conservative treatment group (the best medical treatment). Patients will be followed up at 1, 3, and 6 months after initial treatment. The primary outcomes include the Extended Glasgow Outcome Scale and the Modified Rankin Scale. The secondary outcomes consist of the National Institutes of Health Stroke Scale and the mortality. The Barthel Index(BI) will also be evaluated. The sample size is 100 patients.</p> <p>Discussion</p> <p>The ECMOH trial is a randomized controlled trial designed to evaluate if endoscopic surgery is better than conservative treatment for patients with moderate-volume hematomas in the basal ganglia.</p> <p>Trial registration</p> <p>Chinese Clinical Trial Registry: ChiCTR-TRC-11001614</p> <p>(<url>http://www.chictr.org/en/proj/show.aspx?proj=1618</url>)</p> |
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| format | Article |
| id | doaj.art-2adf2e532cba4c0baa4cac07a8a04e7d |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-12-13T12:13:24Z |
| publishDate | 2012-06-01 |
| publisher | BMC |
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| series | BMC Neurology |
| spelling | doaj.art-2adf2e532cba4c0baa4cac07a8a04e7d2022-12-21T23:46:47ZengBMCBMC Neurology1471-23772012-06-011213410.1186/1471-2377-12-34Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH): study protocol for a randomized controlled trialZan XinLi HaoLiu WenkeFang YuanMa JunpengLan ZhigangLi XiLiu XinYou Chao<p>Abstract</p> <p>Background</p> <p>Spontaneous intracerebral hemorrhage is a disease with high morbidity, high disability rate, high mortality, and high economic burden. Whether patients can benefit from surgical evacuation of hematomas is still controversial, especially for those with moderate-volume hematomas in the basal ganglia. This study is designed to compare the efficacy of endoscopic surgery and conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage.</p> <p>Methods</p> <p>Patients meet the criteria will be randomized into the endoscopic surgery group (endoscopic surgery for hematoma evacuation and the best medical treatment) or the conservative treatment group (the best medical treatment). Patients will be followed up at 1, 3, and 6 months after initial treatment. The primary outcomes include the Extended Glasgow Outcome Scale and the Modified Rankin Scale. The secondary outcomes consist of the National Institutes of Health Stroke Scale and the mortality. The Barthel Index(BI) will also be evaluated. The sample size is 100 patients.</p> <p>Discussion</p> <p>The ECMOH trial is a randomized controlled trial designed to evaluate if endoscopic surgery is better than conservative treatment for patients with moderate-volume hematomas in the basal ganglia.</p> <p>Trial registration</p> <p>Chinese Clinical Trial Registry: ChiCTR-TRC-11001614</p> <p>(<url>http://www.chictr.org/en/proj/show.aspx?proj=1618</url>)</p>http://www.biomedcentral.com/1471-2377/12/34Endoscopic surgeryConservative treatmentModerate-volume hematomaSpontaneous basal ganglia hemorrhage |
| spellingShingle | Zan Xin Li Hao Liu Wenke Fang Yuan Ma Junpeng Lan Zhigang Li Xi Liu Xin You Chao Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH): study protocol for a randomized controlled trial BMC Neurology Endoscopic surgery Conservative treatment Moderate-volume hematoma Spontaneous basal ganglia hemorrhage |
| title | Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH): study protocol for a randomized controlled trial |
| title_full | Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH): study protocol for a randomized controlled trial |
| title_fullStr | Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH): study protocol for a randomized controlled trial |
| title_full_unstemmed | Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH): study protocol for a randomized controlled trial |
| title_short | Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH): study protocol for a randomized controlled trial |
| title_sort | endoscopic surgery versus conservative treatment for the moderate volume hematoma in spontaneous basal ganglia hemorrhage ecmoh study protocol for a randomized controlled trial |
| topic | Endoscopic surgery Conservative treatment Moderate-volume hematoma Spontaneous basal ganglia hemorrhage |
| url | http://www.biomedcentral.com/1471-2377/12/34 |
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