OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDREN
A comparative trial including 80 patients at the age of 1–16 years old was performed in order to evaluate efficacy and safety of osmotic laxatives polyethylene glycol with molecular mass of 4000 kDa and lactulose (46 children received polyethylene glycol, 34 — lactulose) in children with chronic fun...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2012-09-01
|
| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/444 |
| _version_ | 1826562026452811776 |
|---|---|
| author | E. A. Kornienko K. M. Komarov M. Yu. Tipikina T. B. Loboda |
| author_facet | E. A. Kornienko K. M. Komarov M. Yu. Tipikina T. B. Loboda |
| author_sort | E. A. Kornienko |
| collection | DOAJ |
| description | A comparative trial including 80 patients at the age of 1–16 years old was performed in order to evaluate efficacy and safety of osmotic laxatives polyethylene glycol with molecular mass of 4000 kDa and lactulose (46 children received polyethylene glycol, 34 — lactulose) in children with chronic functional constipations. The observation period during the treatment lasted for 2 weeks, clinical and laboratory evaluation of the therapy efficacy and safety was carried out. The normalization of stool was achieved on the average in 3 days of treatment in both groups, pain and dyspepsia were arrested in the majority of the patients. Stool consistency was normalized. No side-effects were registered. However in the first days of lactulose treatment there were reliably more complaints on flatulence and rumbling, which passed spontaneously. Lactulose and polyethylene glycol were shown to be effective and safe in treatment of chronic functional constipations in children and can be recommended for usage even in infants.Keywords: children, constipations, lactulose. |
| first_indexed | 2024-03-12T03:41:25Z |
| format | Article |
| id | doaj.art-2ae24cf5cae543f58a52d92b5515212f |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2025-03-14T09:41:31Z |
| publishDate | 2012-09-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-2ae24cf5cae543f58a52d92b5515212f2025-03-02T11:34:04Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352012-09-0111515215510.15690/vsp.v11i5.445444OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDRENE. A. Kornienko0K. M. Komarov1M. Yu. Tipikina2T. B. Loboda3St. Petersburg State Pediatric Medical UniversityChildren Municipal Hospital № 22, St. PetersburgN.F. Filatov Children Clinical Hospital № 5, St. PetersburgSt. Petersburg State Pediatric Medical UniversityA comparative trial including 80 patients at the age of 1–16 years old was performed in order to evaluate efficacy and safety of osmotic laxatives polyethylene glycol with molecular mass of 4000 kDa and lactulose (46 children received polyethylene glycol, 34 — lactulose) in children with chronic functional constipations. The observation period during the treatment lasted for 2 weeks, clinical and laboratory evaluation of the therapy efficacy and safety was carried out. The normalization of stool was achieved on the average in 3 days of treatment in both groups, pain and dyspepsia were arrested in the majority of the patients. Stool consistency was normalized. No side-effects were registered. However in the first days of lactulose treatment there were reliably more complaints on flatulence and rumbling, which passed spontaneously. Lactulose and polyethylene glycol were shown to be effective and safe in treatment of chronic functional constipations in children and can be recommended for usage even in infants.Keywords: children, constipations, lactulose.https://vsp.spr-journal.ru/jour/article/view/444childrenconstipationslactulose |
| spellingShingle | E. A. Kornienko K. M. Komarov M. Yu. Tipikina T. B. Loboda OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDREN Вопросы современной педиатрии children constipations lactulose |
| title | OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDREN |
| title_full | OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDREN |
| title_fullStr | OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDREN |
| title_full_unstemmed | OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDREN |
| title_short | OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDREN |
| title_sort | osmotic laxatives in treatment of chronic constipations in children |
| topic | children constipations lactulose |
| url | https://vsp.spr-journal.ru/jour/article/view/444 |
| work_keys_str_mv | AT eakornienko osmoticlaxativesintreatmentofchronicconstipationsinchildren AT kmkomarov osmoticlaxativesintreatmentofchronicconstipationsinchildren AT myutipikina osmoticlaxativesintreatmentofchronicconstipationsinchildren AT tbloboda osmoticlaxativesintreatmentofchronicconstipationsinchildren |