From Anti-EBV Immune Responses to the EBV Diseasome via Cross-reactivity

From Anti-EBV Immune Responses to the EBV Diseasome via Cross-reactivity

Sequence analyses highlight a massive peptide sharing between immunoreactive Epstein-Barr virus (EBV) epitopes and human proteins that—when mutated, deficient or improperly functioning—associate with tumorigenesis, diabetes, lupus, multiple sclerosis, rheumatoid arthritis, and immunodeficiencies, am...

Full description

Bibliographic Details
Main Authors:	Darja Kanduc, Yehuda Shoenfeld
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2020-08-01
Series:	Global Medical Genetics
Subjects:	ebv epitopes systemic lupus erythematosus cross-reactivity autoimmunity negative selection self-reactive lymphocytes pathogenic autoantibodies
Online Access:	http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1715641

Similar Items

COVID‐19 associated EBV reactivation and effects of ganciclovir treatment
by: Mei Meng, et al.
Published: (2022-04-01)

EBV-Associated Cancer and Autoimmunity: Searching for Therapies
by: Giovanni Capone, et al.
Published: (2015-02-01)

Regulation mechanism of EBV-encoded EBER1 and LMP2A on YAP1 and the impact of YAP1 on the EBV infection status in EBV-associated gastric carcinoma
by: Yujie Sun, et al.
Published: (2024-05-01)

Medical, Genomic, and Evolutionary Aspects of the Peptide Sharing between Pathogens, Primates, and Humans
by: Darja Kanduc, et al.
Published: (2020-08-01)

Epstein-Barr virus (EBV) and systemic lupus erythematosus (SLE) association in serological studies
by: Witold Czyż, et al.
Published: (2025-01-01)

Targeted eradication of EBV-positive cancer cells by CRISPR/dCas9-mediated EBV reactivation in combination with ganciclovir
by: Febri Gunawan Sugiokto, et al.
Published: (2024-07-01)

From Anti-SARS-CoV-2 Immune Responses to COVID-19 via Molecular Mimicry
by: Darja Kanduc
Published: (2020-07-01)

The probable progression of Epstein-Barr virus (EBV) to chronic active EBV/reactivation weakens the immune response and stimulates Cryptococcus neoformans infection, which invariably proves fatal: a case report and review of the literature
by: Gargee Mishra, et al.
Published: (2025-01-01)

Anti-Cytokine Autoantibodies in Systemic Lupus Erythematosus
by: Hwee Siew Howe, et al.
Published: (2019-12-01)

Frequency of EBV Infection in HIV Positives Patients
by: alireza Abdollahi, et al.
Published: (2014-12-01)

Detection of EBV-DNA in serum samples of an immunosuppressed child during a three years follow-up: association of clinical and PCR data with active infection Detecção de EBV-DNA em amostras de soro de criança imunodeprimida durante três anos de seguimento: associação de dados clínicos e de PCR com a infecção ativa
by: Thelma Suely Okay, et al.
Published: (2005-04-01)

Progress in Prophylactic and Therapeutic EBV Vaccine Development Based on Molecular Characteristics of EBV Target Antigens
by: Marija Rozman, et al.
Published: (2022-07-01)

A tumor-binding antibody with cross-reactivity to viral antigens
by: Michael J. Campa, et al.
Published: (2025-02-01)

EBV CHRONIC INFECTIONS
by: Delia Racciatti, et al.
Published: (2010-02-01)

EBV CHRONIC INFECTIONS
by: Eligio Pizzigallo, et al.
Published: (2010-08-01)

EBV DNA increase in COVID-19 patients with impaired lymphocyte subpopulation count
by: Stefania Paolucci, et al.
Published: (2021-03-01)

Anti‐dsDNA, anti‐nucleosome, anti‐C1q, and anti‐histone antibodies as markers of active lupus nephritis and systemic lupus erythematosus disease activity
by: Xiaoying Shang, et al.
Published: (2021-06-01)

Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts
by: Regina Gary, et al.
Published: (2018-05-01)

A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection
by: Ping Li, et al.
Published: (2025-01-01)

EBV AND HIV-RELATED LYMPHOMA
by: Michele Bibas, et al.
Published: (2009-12-01)

EBV AND HIV-RELATED LYMPHOMA
by: Andrea Antinori, et al.
Published: (2009-11-01)

EBV-induced T-cell responses in EBV-specific and nonspecific cancers
by: Qiuting Zhang, et al.
Published: (2023-09-01)

Immunosuppression With Mycophenolate Mofetil Attenuates Hypertension in an Experimental Model of Autoimmune Disease
by: Erin B. Taylor, et al.
Published: (2017-03-01)

Corrigendum: A self-assembled nanoparticle vaccine elicits effective neutralizing antibody response against EBV infection
by: Ping Li, et al.
Published: (2025-02-01)

Clonal heterogeneity of polymorphic B-cell lymphoproliferative disease, EBV-positive, iatrogenic/immune senescence: implications on pathogenesis and treatment
by: Yu-Yan Hwang, et al.
Published: (2022-12-01)

Opportunities to Target the Life Cycle of Epstein-Barr Virus (EBV) in EBV-Associated Lymphoproliferative Disorders
by: James P. Dugan, et al.
Published: (2019-03-01)

Antiribonuclease H2 antibodies are an immune biomarker for systemic lupus erythematosus
by: Kazuhisa Nozawa, et al.
Published: (2017-05-01)

THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS
by: S. M. Noskov, et al.
Published: (2014-07-01)

THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS
by: S. M. Noskov, et al.
Published: (2014-07-01)

Persistent SARS-CoV-2 Infection, EBV, HHV-6 and Other Factors May Contribute to Inflammation and Autoimmunity in Long COVID
by: Aristo Vojdani, et al.
Published: (2023-01-01)

EBV-associated diseases: Current therapeutics and emerging technologies
by: Srishti Chakravorty, et al.
Published: (2022-10-01)

EBV protection‐ and susceptibility‐related HLA alleles and EBV status in the Chinese population: A single‐center study
by: Dina Suolitiken, et al.
Published: (2022-07-01)

Arsenic trioxide inhibits EBV reactivation and promotes cell death in EBV-positive lymphoma cells
by: Qinyan Yin, et al.
Published: (2017-06-01)

Genotypes of Epstein–Barr virus (EBV1/EBV2) in individuals with infectious mononucleosis in the metropolitan area of Belém, Brazil, between 2005 and 2016
by: Talita Antonia Furtado Monteiro, et al.
Published: (2020-07-01)

Clinical significance and different strategies for re-elevation of plasma EBV-DNA during treatment in pediatric EBV-associated hemophagocytic lymphohistiocytosis
by: Wenzhi Zhang, et al.
Published: (2024-09-01)

Syntropy in Children with EBV Infection
by: L.A. Khodak, et al.
Published: (2015-05-01)

EBV mononucleosis in children in modern conditions
by: J. K. Hakizimana, et al.
Published: (2020-06-01)

EBV-specific T-cell immunity: relevance for multiple sclerosis
by: Malina Behrens, et al.
Published: (2024-12-01)

Drug-induced lupus: simvastatin or amiodarone? A case report in elderly
by: Mauro Turrin, et al.
Published: (2013-03-01)

A combined antibody and DNA assay for EBV infection in children
by: Yulu Yang, et al.
Published: (2022-08-01)