Challenges of Prevention for a Sustainable Personalized Medicine
The development and implementation of the approaches of personalized medicine for disease prevention are still at infancy, although preventive activities in healthcare represent a key pillar to guarantee health system sustainability. There is an increasing interest in finding informative markers tha...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | Journal of Personalized Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4426/11/4/311 |
| _version_ | 1797537439724601344 |
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| author | Roberta Pastorino Claudia Loreti Silvia Giovannini Walter Ricciardi Luca Padua Stefania Boccia |
| author_facet | Roberta Pastorino Claudia Loreti Silvia Giovannini Walter Ricciardi Luca Padua Stefania Boccia |
| author_sort | Roberta Pastorino |
| collection | DOAJ |
| description | The development and implementation of the approaches of personalized medicine for disease prevention are still at infancy, although preventive activities in healthcare represent a key pillar to guarantee health system sustainability. There is an increasing interest in finding informative markers that indicate the disease risk before the manifestation of the disease (primary prevention) or for early disease detection (secondary prevention). Recently, the systematic collection and study of clinical phenotypes and biomarkers consented to the advance of Rehabilomics in tertiary prevention. It consents to identify relevant molecular and physiological factors that can be linked to plasticity, treatment response, and natural recovery. Implementation of these approaches would open avenues to identify people at high risk and enable new preventive lifestyle interventions or early treatments targeted to their individual genomic profile, personalizing prevention and rehabilitation. The integration of personalized medicine into prevention may benefit citizens, patients, healthcare professionals, healthcare authorities, and industry, and ultimately will seek to contribute to better health and quality of life for Europe’s citizens. |
| first_indexed | 2024-03-10T12:15:11Z |
| format | Article |
| id | doaj.art-2aea747682ca4acfa3172daaf1b29c97 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-10T12:15:11Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-2aea747682ca4acfa3172daaf1b29c972023-11-21T15:51:52ZengMDPI AGJournal of Personalized Medicine2075-44262021-04-0111431110.3390/jpm11040311Challenges of Prevention for a Sustainable Personalized MedicineRoberta Pastorino0Claudia Loreti1Silvia Giovannini2Walter Ricciardi3Luca Padua4Stefania Boccia5Department of Woman and Child Health and Public Health—Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDipartimento di Scienze dell’Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDipartimento di Scienze dell’Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalySezione di Igiene, Dipartimento Universitario di Scienze della Vita e Sanità Pubblica, Università Cattolica del Sacro Cuore, 00168 Rome, ItalyDipartimento di Scienze dell’Invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyDepartment of Woman and Child Health and Public Health—Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, ItalyThe development and implementation of the approaches of personalized medicine for disease prevention are still at infancy, although preventive activities in healthcare represent a key pillar to guarantee health system sustainability. There is an increasing interest in finding informative markers that indicate the disease risk before the manifestation of the disease (primary prevention) or for early disease detection (secondary prevention). Recently, the systematic collection and study of clinical phenotypes and biomarkers consented to the advance of Rehabilomics in tertiary prevention. It consents to identify relevant molecular and physiological factors that can be linked to plasticity, treatment response, and natural recovery. Implementation of these approaches would open avenues to identify people at high risk and enable new preventive lifestyle interventions or early treatments targeted to their individual genomic profile, personalizing prevention and rehabilitation. The integration of personalized medicine into prevention may benefit citizens, patients, healthcare professionals, healthcare authorities, and industry, and ultimately will seek to contribute to better health and quality of life for Europe’s citizens.https://www.mdpi.com/2075-4426/11/4/311personalized medicinepreventionpolygenic risk scorerehabilomics |
| spellingShingle | Roberta Pastorino Claudia Loreti Silvia Giovannini Walter Ricciardi Luca Padua Stefania Boccia Challenges of Prevention for a Sustainable Personalized Medicine Journal of Personalized Medicine personalized medicine prevention polygenic risk score rehabilomics |
| title | Challenges of Prevention for a Sustainable Personalized Medicine |
| title_full | Challenges of Prevention for a Sustainable Personalized Medicine |
| title_fullStr | Challenges of Prevention for a Sustainable Personalized Medicine |
| title_full_unstemmed | Challenges of Prevention for a Sustainable Personalized Medicine |
| title_short | Challenges of Prevention for a Sustainable Personalized Medicine |
| title_sort | challenges of prevention for a sustainable personalized medicine |
| topic | personalized medicine prevention polygenic risk score rehabilomics |
| url | https://www.mdpi.com/2075-4426/11/4/311 |
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