Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate
3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-08-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/20/8/14022 |
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| author | Dahye Lee Sunhwa Park Yoseb Yu Kye Jung Shin Jae Hong Seo |
| author_facet | Dahye Lee Sunhwa Park Yoseb Yu Kye Jung Shin Jae Hong Seo |
| author_sort | Dahye Lee |
| collection | DOAJ |
| description | 3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindole from propiolamidoaryl triflate using a commercially available aryl iodide and arylboronic acid in a simple and efficient way with moderate yield and stereoselectivity. |
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| format | Article |
| id | doaj.art-2aebf9eba21340a3aef0031d2d5525d1 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-17T10:33:15Z |
| publishDate | 2015-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-2aebf9eba21340a3aef0031d2d5525d12022-12-21T21:52:27ZengMDPI AGMolecules1420-30492015-08-01208140221403210.3390/molecules200814022molecules200814022Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl TriflateDahye Lee0Sunhwa Park1Yoseb Yu2Kye Jung Shin3Jae Hong Seo4Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, KoreaIntegrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, KoreaIntegrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, KoreaIntegrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, KoreaIntegrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Korea3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindole from propiolamidoaryl triflate using a commercially available aryl iodide and arylboronic acid in a simple and efficient way with moderate yield and stereoselectivity.http://www.mdpi.com/1420-3049/20/8/140223-(Diarylmethylene)oxindoleone-pot reactionaryl triflatepalladium-catalyzed reaction |
| spellingShingle | Dahye Lee Sunhwa Park Yoseb Yu Kye Jung Shin Jae Hong Seo Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate Molecules 3-(Diarylmethylene)oxindole one-pot reaction aryl triflate palladium-catalyzed reaction |
| title | Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate |
| title_full | Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate |
| title_fullStr | Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate |
| title_full_unstemmed | Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate |
| title_short | Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate |
| title_sort | palladium catalyzed one pot approach to 3 diarylmethylene oxindoles from propiolamidoaryl triflate |
| topic | 3-(Diarylmethylene)oxindole one-pot reaction aryl triflate palladium-catalyzed reaction |
| url | http://www.mdpi.com/1420-3049/20/8/14022 |
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