Antiretinal antibody- proven autoimmune retinopathy
A young female presented with bilateral subacute onset of progressive decrease in night vision and reduced peripheral field of vision. The short duration and rapid progression of symptoms along with the lack of family history of night blindness prompted a diagnosis of autoimmune retinopathy (AIR). F...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=5;spage=416;epage=420;aulast=Abraham |
| _version_ | 1819065821106798592 |
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| author | Sharanya Abraham S Sudharshan Muna Bhende Sudha K Ganesh Sriram Gopal |
| author_facet | Sharanya Abraham S Sudharshan Muna Bhende Sudha K Ganesh Sriram Gopal |
| author_sort | Sharanya Abraham |
| collection | DOAJ |
| description | A young female presented with bilateral subacute onset of progressive decrease in night vision and reduced peripheral field of vision. The short duration and rapid progression of symptoms along with the lack of family history of night blindness prompted a diagnosis of autoimmune retinopathy (AIR). Fundus fluorescein angiography, optical coherence tomography, visual fields, and electroretinogram were suggestive of AIR. A differential diagnosis of retinitis pigmentosa (RP) was also made. Antiretinal autoantibodies were detected in the blood sample. Treatment was with oral steroids and subsequently oral immunosuppressive agents. Visual acuity was maintained, fundus examination reverted to normal, and investigations repeated at every visit were stable with improvement in visual fields. Our case suggests that AIR, if diagnosed early and treated appropriately, may have a good outcome and should be considered in patients with an atypical presentation of RP. |
| first_indexed | 2024-12-21T15:52:33Z |
| format | Article |
| id | doaj.art-2aec8577ef47481eb2974660a1dbf3ba |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-21T15:52:33Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-2aec8577ef47481eb2974660a1dbf3ba2022-12-21T18:58:11ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892017-01-0165541642010.4103/ijo.IJO_838_16Antiretinal antibody- proven autoimmune retinopathySharanya AbrahamS SudharshanMuna BhendeSudha K GaneshSriram GopalA young female presented with bilateral subacute onset of progressive decrease in night vision and reduced peripheral field of vision. The short duration and rapid progression of symptoms along with the lack of family history of night blindness prompted a diagnosis of autoimmune retinopathy (AIR). Fundus fluorescein angiography, optical coherence tomography, visual fields, and electroretinogram were suggestive of AIR. A differential diagnosis of retinitis pigmentosa (RP) was also made. Antiretinal autoantibodies were detected in the blood sample. Treatment was with oral steroids and subsequently oral immunosuppressive agents. Visual acuity was maintained, fundus examination reverted to normal, and investigations repeated at every visit were stable with improvement in visual fields. Our case suggests that AIR, if diagnosed early and treated appropriately, may have a good outcome and should be considered in patients with an atypical presentation of RP.http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=5;spage=416;epage=420;aulast=AbrahamAntiretinal antibodiesautoimmune retinopathyimmunosuppressive agentssteroidsvisual fields |
| spellingShingle | Sharanya Abraham S Sudharshan Muna Bhende Sudha K Ganesh Sriram Gopal Antiretinal antibody- proven autoimmune retinopathy Indian Journal of Ophthalmology Antiretinal antibodies autoimmune retinopathy immunosuppressive agents steroids visual fields |
| title | Antiretinal antibody- proven autoimmune retinopathy |
| title_full | Antiretinal antibody- proven autoimmune retinopathy |
| title_fullStr | Antiretinal antibody- proven autoimmune retinopathy |
| title_full_unstemmed | Antiretinal antibody- proven autoimmune retinopathy |
| title_short | Antiretinal antibody- proven autoimmune retinopathy |
| title_sort | antiretinal antibody proven autoimmune retinopathy |
| topic | Antiretinal antibodies autoimmune retinopathy immunosuppressive agents steroids visual fields |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2017;volume=65;issue=5;spage=416;epage=420;aulast=Abraham |
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