The principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICU

Abstract In 2011, a multicenter group spearheaded at the University of Virginia demonstrated reduced mortality from real-time continuous cardiorespiratory monitoring in the neonatal ICU using what we now call Artificial Intelligence, Big Data, and Machine Learning. The large, randomized heart rate c...

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Main Author: J. Randall Moorman
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-022-00584-y
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author J. Randall Moorman
author_facet J. Randall Moorman
author_sort J. Randall Moorman
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description Abstract In 2011, a multicenter group spearheaded at the University of Virginia demonstrated reduced mortality from real-time continuous cardiorespiratory monitoring in the neonatal ICU using what we now call Artificial Intelligence, Big Data, and Machine Learning. The large, randomized heart rate characteristics trial made real, for the first time that we know of, the promise that early detection of illness would allow earlier and more effective intervention and improved patient outcomes. Currently, though, we hear as much of failures as we do of successes in the rapidly growing field of predictive analytics monitoring that has followed. This Perspective aims to describe the principles of how we developed heart rate characteristics monitoring for neonatal sepsis and then applied them throughout adult ICU and hospital medicine. It primarily reflects the work since the 1990s of the University of Virginia group: the theme is that sudden and catastrophic deteriorations can be preceded by subclinical but measurable physiological changes apparent in the continuous cardiorespiratory monitoring and electronic health record.
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spelling doaj.art-2af7c0d2dff4400487e5fb34f028b0eb2023-12-03T00:33:53ZengNature Portfolionpj Digital Medicine2398-63522022-03-01511610.1038/s41746-022-00584-yThe principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICUJ. Randall Moorman0Cardiovascular Division, Department of Internal Medicine, Center for Advanced Medical Analytics, University of VirginiaAbstract In 2011, a multicenter group spearheaded at the University of Virginia demonstrated reduced mortality from real-time continuous cardiorespiratory monitoring in the neonatal ICU using what we now call Artificial Intelligence, Big Data, and Machine Learning. The large, randomized heart rate characteristics trial made real, for the first time that we know of, the promise that early detection of illness would allow earlier and more effective intervention and improved patient outcomes. Currently, though, we hear as much of failures as we do of successes in the rapidly growing field of predictive analytics monitoring that has followed. This Perspective aims to describe the principles of how we developed heart rate characteristics monitoring for neonatal sepsis and then applied them throughout adult ICU and hospital medicine. It primarily reflects the work since the 1990s of the University of Virginia group: the theme is that sudden and catastrophic deteriorations can be preceded by subclinical but measurable physiological changes apparent in the continuous cardiorespiratory monitoring and electronic health record.https://doi.org/10.1038/s41746-022-00584-y
spellingShingle J. Randall Moorman
The principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICU
npj Digital Medicine
title The principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICU
title_full The principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICU
title_fullStr The principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICU
title_full_unstemmed The principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICU
title_short The principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICU
title_sort principles of whole hospital predictive analytics monitoring for clinical medicine originated in the neonatal icu
url https://doi.org/10.1038/s41746-022-00584-y
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