Dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgery
BackgroundDexmedetomidine has a sedative analgesic property without respiratory depression. This study evaluated the efficacy of dexmedetomidine as an appropriate sedative drug for monitored anesthesia care (MAC) in outpatients undergoing cataract surgery on both eyes compared with combination of pr...
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| Format: | Article |
| Language: | English |
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Korean Society of Anesthesiologists
2011-12-01
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| Series: | Korean Journal of Anesthesiology |
| Subjects: | |
| Online Access: | http://ekja.org/upload/pdf/kjae-61-453.pdf |
| _version_ | 1819212008526970880 |
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| author | Hyo-Seok Na In-Ae Song Hong-Sik Park Jung-Won Hwang Sang-Hwan Do Chong-Soo Kim |
| author_facet | Hyo-Seok Na In-Ae Song Hong-Sik Park Jung-Won Hwang Sang-Hwan Do Chong-Soo Kim |
| author_sort | Hyo-Seok Na |
| collection | DOAJ |
| description | BackgroundDexmedetomidine has a sedative analgesic property without respiratory depression. This study evaluated the efficacy of dexmedetomidine as an appropriate sedative drug for monitored anesthesia care (MAC) in outpatients undergoing cataract surgery on both eyes compared with combination of propofol and alfentanil.MethodsThirty-one eligible patients were randomly divided into two groups on the first operation day. Dexmedetomidine was administered in group D at 0.6 µg/kg/h, and propofol and alfentanil was infused concomitantly in group P at a rate of 2 mg/kg/h and 20 µg/kg/h, respectively. Sedation was titrated at Ramsay sedation score 3. Iowa satisfaction with anesthesia scale (ISAS) of the patients was evaluated postoperatively. Systolic blood pressure (SBP), heart rate (HR), respiration rate (RR), and peripheral oxygen saturation (SpO2) were recorded throughout the surgery. For the second operation, the group assignments were exchanged.ResultsPostoperative ISAS was 50.3 (6.2) in group D and 42.7 (8.7) in group P, which was statistically significant (P < 0.001). SBP was significantly lower in group D compared with group P from the beginning of the operation. HR, RR, and SpO2 were comparable between the two groups. There were 8 cases (25.8%) of hypertension in group P, and 1 case (3.2%) in group D (P < 0.05). In contrast, 1 case (3.2%) of hypotension and 1 case (3.2%) of bradycardia occurred in group D.ConclusionsCompared with the combined use of propofol and alfentanil, dexmedetomidine could be used appropriately for MAC in cataract surgery with better satisfaction from the patients and a more stable cardiovascular state. |
| first_indexed | 2024-12-23T06:36:08Z |
| format | Article |
| id | doaj.art-2af81d42b86e40b3852db931cb12a802 |
| institution | Directory Open Access Journal |
| issn | 2005-6419 2005-7563 |
| language | English |
| last_indexed | 2024-12-23T06:36:08Z |
| publishDate | 2011-12-01 |
| publisher | Korean Society of Anesthesiologists |
| record_format | Article |
| series | Korean Journal of Anesthesiology |
| spelling | doaj.art-2af81d42b86e40b3852db931cb12a8022022-12-21T17:56:48ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632011-12-0161645345910.4097/kjae.2011.61.6.4537234Dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgeryHyo-Seok Na0In-Ae Song1Hong-Sik Park2Jung-Won Hwang3Sang-Hwan Do4Chong-Soo Kim5Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.Department of Anesthesiology and Pain Medicine, Boramae Medical Center, Seoul, Korea.BackgroundDexmedetomidine has a sedative analgesic property without respiratory depression. This study evaluated the efficacy of dexmedetomidine as an appropriate sedative drug for monitored anesthesia care (MAC) in outpatients undergoing cataract surgery on both eyes compared with combination of propofol and alfentanil.MethodsThirty-one eligible patients were randomly divided into two groups on the first operation day. Dexmedetomidine was administered in group D at 0.6 µg/kg/h, and propofol and alfentanil was infused concomitantly in group P at a rate of 2 mg/kg/h and 20 µg/kg/h, respectively. Sedation was titrated at Ramsay sedation score 3. Iowa satisfaction with anesthesia scale (ISAS) of the patients was evaluated postoperatively. Systolic blood pressure (SBP), heart rate (HR), respiration rate (RR), and peripheral oxygen saturation (SpO2) were recorded throughout the surgery. For the second operation, the group assignments were exchanged.ResultsPostoperative ISAS was 50.3 (6.2) in group D and 42.7 (8.7) in group P, which was statistically significant (P < 0.001). SBP was significantly lower in group D compared with group P from the beginning of the operation. HR, RR, and SpO2 were comparable between the two groups. There were 8 cases (25.8%) of hypertension in group P, and 1 case (3.2%) in group D (P < 0.05). In contrast, 1 case (3.2%) of hypotension and 1 case (3.2%) of bradycardia occurred in group D.ConclusionsCompared with the combined use of propofol and alfentanil, dexmedetomidine could be used appropriately for MAC in cataract surgery with better satisfaction from the patients and a more stable cardiovascular state.http://ekja.org/upload/pdf/kjae-61-453.pdfcataractdexmedetomidinemonitored anesthesia carepropofol |
| spellingShingle | Hyo-Seok Na In-Ae Song Hong-Sik Park Jung-Won Hwang Sang-Hwan Do Chong-Soo Kim Dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgery Korean Journal of Anesthesiology cataract dexmedetomidine monitored anesthesia care propofol |
| title | Dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgery |
| title_full | Dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgery |
| title_fullStr | Dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgery |
| title_full_unstemmed | Dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgery |
| title_short | Dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgery |
| title_sort | dexmedetomidine is effective for monitored anesthesia care in outpatients undergoing cataract surgery |
| topic | cataract dexmedetomidine monitored anesthesia care propofol |
| url | http://ekja.org/upload/pdf/kjae-61-453.pdf |
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