FUT1-mediated terminal fucosylation acts as a new target to attenuate renal fibrosis
Abstract Backgrounds Renal fibrosis is a common pathologic process of most chronic kidney diseases (CKDs), becoming one of the major public health problems worldwide. Terminal fucosylation plays an important role in physiological homeostasis and pathological development. The present study aimed to e...
Main Authors: | Jialiang Luo, Kaifeng Mao, Zhengyumeng Zhu, Junli Ye, Lei Li, Di Wang, Jia Zhou, Fenwang Lin, Juan Li, Junsheng Ye |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-04-01
|
Series: | Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s10020-023-00639-0 |
Similar Items
-
FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation
by: Lingnan He, et al.
Published: (2023-03-01) -
Role of Fucosylation in Cancer
by: Kun ZHANG, et al.
Published: (2016-11-01) -
Intestinal epithelium-specific Fut2 deficiency promotes colorectal cancer through down-regulating fucosylation of MCAM
by: Weijun Wang, et al.
Published: (2023-02-01) -
Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling
by: Qian Huang, et al.
Published: (2022-09-01) -
Inhibitory Effects of 3-Cyclopropylmethoxy-4-(difluoromethoxy) Benzoic Acid on TGF-β1-Induced Epithelial–Mesenchymal Transformation of In Vitro and Bleomycin-Induced Pulmonary Fibrosis In Vivo
by: Tianxiao Sun, et al.
Published: (2023-03-01)