Optic nerve cavitations in glaucoma suspect and glaucoma patients
Purpose: Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT). Ob...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993622004790 |
| _version_ | 1811207469510164480 |
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| author | Bennett Y. Hong Brad Fortune Robert M. Kinast Claude F. Burgoyne Jack P. Rees Steven L. Mansberger |
| author_facet | Bennett Y. Hong Brad Fortune Robert M. Kinast Claude F. Burgoyne Jack P. Rees Steven L. Mansberger |
| author_sort | Bennett Y. Hong |
| collection | DOAJ |
| description | Purpose: Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT). Observations: OCT imaging showed cavitations in 5 eyes of 4 patients with an initial diagnosis of glaucoma or glaucoma suspect. The cavitations were seen as hyporeflective spaces that are sharply delineated from surrounding tissue. They were centered inferonasally, anterior to the lamina cribosa, and at least partially within the Bruch's membrane opening (BMO). They extended from 3 to 6 clock hours. Conclusion: AND IMPORTANCE: We describe a new OCT finding in patients with a diagnosis of glaucoma and glaucoma suspect. While previous reports describe cavitations in the choroid in patients with pathological myopia, our patients had minimal refractive error and the cavitations were located within the optic nerve. We will examine these patients over time to determine the impact of this finding on longitudinal changes in structure and function. |
| first_indexed | 2024-04-12T04:03:48Z |
| format | Article |
| id | doaj.art-2af986103f5b4e2c92980f9fe9b99cae |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-04-12T04:03:48Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-2af986103f5b4e2c92980f9fe9b99cae2022-12-22T03:48:39ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-12-0128101733Optic nerve cavitations in glaucoma suspect and glaucoma patientsBennett Y. Hong0Brad Fortune1Robert M. Kinast2Claude F. Burgoyne3Jack P. Rees4Steven L. Mansberger5Legacy Devers Eye Institute, 1040 N.W. 22nd Ave, Good Samaritan Building 2, Portland, OR, 97210, USALegacy Devers Eye Institute, 1040 N.W. 22nd Ave, Good Samaritan Building 2, Portland, OR, 97210, USALegacy Devers Eye Institute, 1040 N.W. 22nd Ave, Good Samaritan Building 2, Portland, OR, 97210, USALegacy Devers Eye Institute, 1040 N.W. 22nd Ave, Good Samaritan Building 2, Portland, OR, 97210, USALegacy Devers Eye Institute, 1040 N.W. 22nd Ave, Good Samaritan Building 2, Portland, OR, 97210, USACorresponding author. Legacy Devers Eye Institute. 1040 N.W. 22nd Ave., Suite 200, Portland, OR, 97210, USA.; Legacy Devers Eye Institute, 1040 N.W. 22nd Ave, Good Samaritan Building 2, Portland, OR, 97210, USAPurpose: Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT). Observations: OCT imaging showed cavitations in 5 eyes of 4 patients with an initial diagnosis of glaucoma or glaucoma suspect. The cavitations were seen as hyporeflective spaces that are sharply delineated from surrounding tissue. They were centered inferonasally, anterior to the lamina cribosa, and at least partially within the Bruch's membrane opening (BMO). They extended from 3 to 6 clock hours. Conclusion: AND IMPORTANCE: We describe a new OCT finding in patients with a diagnosis of glaucoma and glaucoma suspect. While previous reports describe cavitations in the choroid in patients with pathological myopia, our patients had minimal refractive error and the cavitations were located within the optic nerve. We will examine these patients over time to determine the impact of this finding on longitudinal changes in structure and function.http://www.sciencedirect.com/science/article/pii/S2451993622004790Optic nerve cavitationsIntrachoroidal cavitationsLamina cribosaGlaucomaImagingOptical coherence tomography |
| spellingShingle | Bennett Y. Hong Brad Fortune Robert M. Kinast Claude F. Burgoyne Jack P. Rees Steven L. Mansberger Optic nerve cavitations in glaucoma suspect and glaucoma patients American Journal of Ophthalmology Case Reports Optic nerve cavitations Intrachoroidal cavitations Lamina cribosa Glaucoma Imaging Optical coherence tomography |
| title | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
| title_full | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
| title_fullStr | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
| title_full_unstemmed | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
| title_short | Optic nerve cavitations in glaucoma suspect and glaucoma patients |
| title_sort | optic nerve cavitations in glaucoma suspect and glaucoma patients |
| topic | Optic nerve cavitations Intrachoroidal cavitations Lamina cribosa Glaucoma Imaging Optical coherence tomography |
| url | http://www.sciencedirect.com/science/article/pii/S2451993622004790 |
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