Urinary Tract Infections in the Emergency Department: Which Antibiotics are Most Appropriate?
Aim: Urinary tract infections (UTIs) are frequently seen and also empirically treated in the emergency department (ED). It is known that the antimicrobial resistance of uropathogens is increasing worldwide. Because geographical location plays an important role in antimicrobial resistance and can be...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2016-09-01
|
| Series: | Eurasian Journal of Emergency Medicine |
| Subjects: | |
| Online Access: |
http://akademikaciltip.com/archives/archive-detail/article-preview/urinary-tract-nfections-in-the-emergency-departmen/21810
|
| _version_ | 1797907285502066688 |
|---|---|
| author | İbrahim Toker Turgay Yılmaz Kılıç Şükran Köse Murat Yeşilaras Orkun Ünek Serkan Hacar Ayşin Kılınç Toker |
| author_facet | İbrahim Toker Turgay Yılmaz Kılıç Şükran Köse Murat Yeşilaras Orkun Ünek Serkan Hacar Ayşin Kılınç Toker |
| author_sort | İbrahim Toker |
| collection | DOAJ |
| description | Aim: Urinary tract infections (UTIs) are frequently seen and also empirically treated in the emergency department (ED). It is known that the antimicrobial resistance of uropathogens is increasing worldwide. Because geographical location plays an important role in antimicrobial resistance and can be used as a guide for treatment, regional studies are particularly important. The aim of this study is to analyze the urine cultures performed at our ED.Materials and Methods: We investigated the medical records of 4,493 patients who were requested to give urine samples for culture at the ED of the Tepecik Training and Research Hospital between 2010 and 2014.Results: In our study, 47.3% cultures were positive, and the most frequent microorganism was found to be Escherichia coli (E. coli) (66.7%). Trimethoprim/sulfamethoxazole (TMP-SMX) and ciprofloxacin resistance rates were detected as 44.8% and 36.8%, respectively; further, nitrofurantoin and fosfomycin resistance rates were detected as 13.3% and 7.6%, respectively. The relationship of nitrite positivity with the reproduction of pathogens was found to be stronger than that of leukocyte esterase (LE).Conclusion: For our region, for the empirical treatment of uncomplicated UTIs, fosfomycin and nitrofurantoin must be considered as the first-line agents. Because of the increasing ratio of antibiotic resistance, urinary culture samples must be arranged for in the ED itself where administering first-line treatment has mostly been initiated. |
| first_indexed | 2024-04-10T10:34:06Z |
| format | Article |
| id | doaj.art-2afc31ae3cfc4259b2aca6ce6db77e45 |
| institution | Directory Open Access Journal |
| issn | 2149-5807 2149-6048 |
| language | English |
| last_indexed | 2024-04-10T10:34:06Z |
| publishDate | 2016-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Eurasian Journal of Emergency Medicine |
| spelling | doaj.art-2afc31ae3cfc4259b2aca6ce6db77e452023-02-15T16:20:58ZengGalenos YayineviEurasian Journal of Emergency Medicine2149-58072149-60482016-09-0115312613010.5152/eajem.2016.2485513049054Urinary Tract Infections in the Emergency Department: Which Antibiotics are Most Appropriate?İbrahim Toker0Turgay Yılmaz Kılıç1Şükran Köse2Murat Yeşilaras3Orkun Ünek4Serkan Hacar5Ayşin Kılınç Toker6 Department of Emergency Medicine, Tepecik Training and Education Hospital, İzmir, Turkey Department of Emergency Medicine, Tepecik Training and Education Hospital, İzmir, Turkey Department of Infectious Diseases and Clinical Microbiology, Tepecik Training and Education Hospital, İzmir, Turkey Department of Emergency Medicine, Tepecik Training and Education Hospital, İzmir, Turkey Department of Emergency Medicine, Tepecik Training and Education Hospital, İzmir, Turkey Department of Emergency Medicine, Tepecik Training and Education Hospital, İzmir, Turkey Department of Infectious Diseases and Clinical Microbiology, Tepecik Training and Education Hospital, İzmir, Turkey Aim: Urinary tract infections (UTIs) are frequently seen and also empirically treated in the emergency department (ED). It is known that the antimicrobial resistance of uropathogens is increasing worldwide. Because geographical location plays an important role in antimicrobial resistance and can be used as a guide for treatment, regional studies are particularly important. The aim of this study is to analyze the urine cultures performed at our ED.Materials and Methods: We investigated the medical records of 4,493 patients who were requested to give urine samples for culture at the ED of the Tepecik Training and Research Hospital between 2010 and 2014.Results: In our study, 47.3% cultures were positive, and the most frequent microorganism was found to be Escherichia coli (E. coli) (66.7%). Trimethoprim/sulfamethoxazole (TMP-SMX) and ciprofloxacin resistance rates were detected as 44.8% and 36.8%, respectively; further, nitrofurantoin and fosfomycin resistance rates were detected as 13.3% and 7.6%, respectively. The relationship of nitrite positivity with the reproduction of pathogens was found to be stronger than that of leukocyte esterase (LE).Conclusion: For our region, for the empirical treatment of uncomplicated UTIs, fosfomycin and nitrofurantoin must be considered as the first-line agents. Because of the increasing ratio of antibiotic resistance, urinary culture samples must be arranged for in the ED itself where administering first-line treatment has mostly been initiated. http://akademikaciltip.com/archives/archive-detail/article-preview/urinary-tract-nfections-in-the-emergency-departmen/21810 Urinary tract infectionemergency medicineantibiotic resistance |
| spellingShingle | İbrahim Toker Turgay Yılmaz Kılıç Şükran Köse Murat Yeşilaras Orkun Ünek Serkan Hacar Ayşin Kılınç Toker Urinary Tract Infections in the Emergency Department: Which Antibiotics are Most Appropriate? Eurasian Journal of Emergency Medicine Urinary tract infection emergency medicine antibiotic resistance |
| title | Urinary Tract Infections in the Emergency Department: Which Antibiotics are Most Appropriate? |
| title_full | Urinary Tract Infections in the Emergency Department: Which Antibiotics are Most Appropriate? |
| title_fullStr | Urinary Tract Infections in the Emergency Department: Which Antibiotics are Most Appropriate? |
| title_full_unstemmed | Urinary Tract Infections in the Emergency Department: Which Antibiotics are Most Appropriate? |
| title_short | Urinary Tract Infections in the Emergency Department: Which Antibiotics are Most Appropriate? |
| title_sort | urinary tract infections in the emergency department which antibiotics are most appropriate |
| topic | Urinary tract infection emergency medicine antibiotic resistance |
| url |
http://akademikaciltip.com/archives/archive-detail/article-preview/urinary-tract-nfections-in-the-emergency-departmen/21810
|
| work_keys_str_mv | AT ibrahimtoker urinarytractinfectionsintheemergencydepartmentwhichantibioticsaremostappropriate AT turgayyılmazkılıc urinarytractinfectionsintheemergencydepartmentwhichantibioticsaremostappropriate AT sukrankose urinarytractinfectionsintheemergencydepartmentwhichantibioticsaremostappropriate AT muratyesilaras urinarytractinfectionsintheemergencydepartmentwhichantibioticsaremostappropriate AT orkununek urinarytractinfectionsintheemergencydepartmentwhichantibioticsaremostappropriate AT serkanhacar urinarytractinfectionsintheemergencydepartmentwhichantibioticsaremostappropriate AT aysinkılınctoker urinarytractinfectionsintheemergencydepartmentwhichantibioticsaremostappropriate |