Casein Kinase-2 Interacting Protein-1 Regulates Physiological Cardiac Hypertrophy via Inhibition of Histone Deacetylase 4 Phosphorylation

Casein Kinase-2 Interacting Protein-1 Regulates Physiological Cardiac Hypertrophy via Inhibition of Histone Deacetylase 4 Phosphorylation

Different kinds of mechanical stimuli acting on the heart lead to different myocardial phenotypes. Physiological stress, such as exercise, leads to adaptive cardiac hypertrophy, which is characterized by a normal cardiac structure and improved cardiac function. Pathological stress, such as sustained...

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Bibliographic Details
Main Authors: Yinlong Zhao, Shukuan Ling, Guohui Zhong, Yuheng Li, Jianwei Li, Ruikai Du, Xiaoyan Jin, Dingsheng Zhao, Zizhong Liu, Guanghan Kan, Yan-Zhong Chang, Yingxian Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
CKIP-1
swimming
physiological cardiac hypertrophy
pathological cardiac remodeling
HDAC4
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.678863/full

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