Are mast cells instrumental for fibrotic diseases?

Are mast cells instrumental for fibrotic diseases?

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disorder of unknown etiology characterised by accumulation of lung fibroblasts and extracellular matrix deposition, ultimately leading to compromised tissue architecture and lung function capacity. IPF has a heterogeneous clinical course; however...

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Bibliographic Details
Main Authors:	Catherine eOvered-Sayer, Laura eRapley, Tomas eMustelin, Deborah Lee Clarke
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-01-01
Series:	Frontiers in Pharmacology
Subjects:	Fibrosis Idiopathic Pulmonary Fibrosis Lung Mast Cells TGF-beta
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00174/full

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